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Size-Exclusion Chromatography
Grenhas, Madalena; Lopes, Raquel; Ferreira, Bruna Velosa; Barahona, Filipa; João, Cristina; Carneiro, Emilie ArnaultFunding Information: The authors express their gratitude to the Electron Microscopy Unit of Instituto Gulbenkian de Ci\u00EAncia (IGC) for the acquisition of the EV images. Additionally, we extend our appreciation to Carolina Pestana MSc for her contribution to the statistical analysis of this study, to the Systems Oncology Research Group (Champalimaud Foundation) for granting access to the required equipment f...
Correction to
Ferreira, Bruna; Caetano, Joana; Barahona, Filipa; Lopes, Raquel; Carneiro, Emilie; Costa-Silva, Bruno; João, CristinaFunding Information: Funding This research was funded by the Funda\u00E7\u00E3o para a Ci\u00EAncia e Tecnologia \u2013 FCT (Research Grant PTDC/MEC-HEM/30315/2017). Publisher Copyright: © The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature 2024.; We mistakenly forgot to mention the funding for this paper. Funding This research was funded by the Fundação para a Ciênci...
Review of Piezoelectrical Materials Potentially Useful for Peripheral Nerve Repair
Casal, Diogo; Casimiro, M. H.; Ferreira, Luís M.; Leal, J. P.; Rodrigues, Gabriela; Lopes, Raquel; Moura, Diogo Lino; Gonçalves, Luís; Lago, João B.Funding Information: This research was funded by the International Atomic Energy Agency: Research Contract No. 24415 (CRP F23035). Authors acknowledge FCT—Fundação para a Ciência e a Tecnologia I.P. for the national funds in the scope of the project UIDB/04349/2020+UIDP/04349/2020, UIDB/00100/2020+LA/P/0056/2020 and UIDB/00329/2020. Publisher Copyright: © 2023 by the authors.; It has increasingly been recognize...
Isothermal denaturation fluorimetry vs differential scanning fluorimetry as too...
Leandro, Paula; Lino, Paulo R.; Lopes, Raquel; Leandro, João; Amaro, Mariana P.; Sousa, Paulo; Vicente, João B.; Almeida, António J.Funding Information: Authors acknowledge Sofarimex, Indústria Química e Farmacêutica SA, Portugal, for all the support concerning freeze-drying studies. This work was supported by FEDER and Fundação para a Ciência e a Tecnologia, I. P. through iMED.ULisboa (Projects UIDB/04138/2020 and UIDP/04138/2020), iNOVA4Health (UIDB/04462/2020, UIDP/04462/2020) and LS4FUTURE Associated Laboratory (LA/P/0087/2020) and rese...
Patient-Derived Multiple Myeloma 3D Models for Personalized Medicine—Are We The...
Lourenço, Diana; Lopes, Raquel; Pestana, Carolina; Queirós, Ana C.; João, Cristina; Carneiro, Emilie ArnaultFunding Information: This work was supported by Fundação para a Ciência e a Tecnologia (FCT), research grant number PTDC/MED-ONC/1215/2021/PT. Funding Information: The authors thank FCT and the Champalimaud Foundation for funding. Publisher Copyright: © 2022 by the authors.; Despite the wide variety of existing therapies, multiple myeloma (MM) remains a disease with dismal prognosis. Choosing the right treatmen...
Patient-Derived Extracellular Vesicles Proteins as New Biomarkers in Multiple M...
Ferreira, Bruna Velosa; Carneiro, Emilie Arnault; Pestana, Carolina; Barahona, Filipa; Caetano, Joana; Lopes, Raquel; Lúcio, Paulo; Neves, ManuelFunding Information: This research was funded by the Champalimaud Foundation; by the Fundação para a Ciência e Tecnologia – FCT (Research Grant PTDC/MEC-HEM/30315/2017) and by Sociedade Portuguesa de Hematologia -SPH (Initiation to Investigation Grant 2018).; Multiple myeloma (MM) is a hematological malignancy of clonal antibody–secreting plasma cells (PCs). MM diagnosis and risk stratification rely on bone mar...
Multiple Myeloma-Derived Extracellular Vesicles Modulate the Bone Marrow Immune...
Lopes, Raquel; Caetano, Joana; Barahona, Filipa; Pestana, Carolina; Ferreira, Bruna Velosa; Lourenço, Diana; Queirós, Ana C.; Bilreiro, CarlosFunding Information: This work was supported by Portuguese national funds, through FCT—Fundação para a Ciência e Tecnologia—in the context of the projects PDTC/MEC-HEM/30315/2017 and PCDC/MED-ONC/1215/2021, and by GILEAD GÉNESE (project PGG/058/2019). RL received a fellowship funded by FCT (2020.4875.BD). This work was also supported by the research infrastructure CONGENTO, co-financed by Lisboa Regional Operat...
The immune microenvironment in multiple myeloma
Lopes, Raquel; Caetano, Joana; Ferreira, Bruna; Barahona, Filipa; Carneiro, Emilie Arnault; João, CristinaFunding: This research was funded by Fundação para a Ciência e Tecnologia (FCT), PTDC/MECHEM/30315/2017.; Multiple myeloma (MM) is one of the most prevalent hematological cancers worldwide, characterized by the clonal expansion of neoplastic plasma cells in the bone marrow (BM). A combination of factors is implicated in disease progression, including BM immune microenvironment changes. Increasing evidence sugge...
Boosting immunity against multiple myeloma
Lopes, Raquel; Ferreira, Bruna Velosa; Caetano, Joana; Barahona, Filipa; Carneiro, Emilie Arnault; João, CristinaFunding: This research was funded by Fundação para a Ciência e Tecnologia (FCT), PTDC/MECHEM/30315/2017 and UIDB/04443/2020; Despite the improvement of patient’s outcome obtained by the current use of immunomod-ulatory drugs, proteasome inhibitors or anti-CD38 monoclonal antibodies, multiple myeloma (MM) remains an incurable disease. More recently, the testing in clinical trials of novel drugs such as anti-BCMA...