3 documents found, page 1 of 1
Eugenol as a promising molecule for the treatment of dermatitis: antioxidant an...
Lopes, Amanda de Araújo; Fonseca, Francisco Noé da; Rocha, Talita Magalhães; Freitas, Lyara Barbosa de; Araújo, Emmanuel Vinicius OliveiraContact dermatitis produces an inflammatory reaction primarily via stimulation of keratinocytes and cells of the immune system, which promote the release of cytokines, reactive oxygen species (ROS), and other chemical mediators. Eugenol (EUG, phenylpropanoid of essential oils) has attracted attention due to its anti-inflammatory properties, as well as antioxidant effect. On the other hand, it is volatile and in...
Cytotoxicity and DNA damage in the neutrophils of patients with sickle cell ana...
Pedrosa, Alano Martins; Barbosa, Maritza Cavalcante; Santos, Thayna Nogueira dos; Leal, Luzia Kalyne Almeida Moreira; Lopes, Amanda de AraújoA hidroxiuréia (HU) constitui o avanço mais importante no tratamento da anemia falciforme (AF) por prevenir complicações e aumentar a qualidade de vida dos pacientes. Entretanto, alguns aspectos do tratamento com HU permanecem obscuros, incluindo a sua ação e potencial toxicidade em outras células sanguíneas, tais como neutrófilos. Este estudo utilizou a mensuração da lactato desidrogenase (LDH) e do metil tiaz...
Avaliação da atividade antiinflamatória e antioxidante das cápsulas do extrato ...
Lopes, Amanda de AraújoThe stem bark of Amburana cearensis AC Smith, popularly known as cumaru, is used to treat respiratory diseases like bronchitis and asthma. Previous pharmacological studies showed the anti-inflammatory, antinociceptive and antioxidant, and / or muscle relaxant activities of the the extract and isolated molecules from cumaru, including coumarin (CM) and amburoside A (AMB). Given the above, the objective of this s...