32 documents found, page 1 of 4

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Update on infections with Thelazia callipaeda in European wildlife and a report...

Lopes, Ana Filipa; Ferreira, Mariana Ribeiro; Vale, Beatriz do; Santos, Marlene; Silveira, Inês; Claudino, Sofia; Martins, Manuel; Brida, Telma

Thelazia callipaeda, also known as the “oriental eye worm”, is a zoonotic parasitic nematode with a wide range of hosts, particularly wild and domestic carnivores, but also lagomorphs and humans. Currently, ocular thelaziosis presents an expanding distribution range throughout Europe, including Portugal. This study provides an update on T. callipaeda infection reports (30 studies) in European wildlife comprisin...


Hunting for answers: Assessing Brucella spp. seroprevalence and risks in red de...

Pires, Humberto; Cardoso, Luís; Lopes, Ana Patrícia; Fontes, Maria da Conceição; Silva, Sérgio Santos; Matos, Manuela; Pintado, Cristina Santos

Between 2016 and 2023, a cross-sectional study was conducted in the central region of Portugal in order to better understand the epidemiology and public health risks resulting from the handling and consumption of game animals infected with Brucella spp. The seroprevalence and risk factors for Brucella spp. seropositivity were evaluated. Antibodies against Brucella spp. were determined using a commercial enzyme-...


Serological evidence of antibodies to Flaviviridae in wild birds in Portugal

Loureiro, Filipa; Cardoso, Luís; Matos, Ana Cristina; Pintado, Cristina Santos; Silva, Filipe; Ferreira, Mariana; Brandão, Ricardo; Lopes, Carolina

Emerging infectious diseases are a major threat to biodiversity and an important public health issue. Flaviviruses are the cause of several emerging vector-borne zoonotic arboviruses whose distribution is currently increasing in Europe. The evidence that West Nile virus (WNV) circulates in resident and migratory species has implications for both animal and public health and should therefore be studied in depth....


Molecular evidence of sporadic Coxiella burnetii excretion in sheep milk, centr...

Pires, Humberto; Silva, Sérgio Santos; Cruz, Andreia V.S.; Cardoso, Luís; Lopes, Ana Patrícia; Pereira, Maria A.; Nóbrega, Carmen; Mega, Ana Cristina

Coxiella burnetii is the etiologic agent of Q fever, a worldwide zoonosis. Cattle, sheep and goats are considered the main reservoirs of the disease. Transmission to humans occurs mainly through the inhalation of infectious aerosols from milk, faeces, urine, and birth products from infected ruminants. In this study, a 2-year longitudinal approach was performed to ascertain the excretion of C. burnetii in bulk t...


Molecular evidence of sporadic Coxiella burnetii excretion in sheep milk, centr...

Pires, Humberto; Santos-Silva, Sérgio; Cruz, Andreia V.S.; Cardoso, Luís; Lopes, Ana Patrícia; Pereira, Maria; Nóbrega, Carmen; Mega, Cristina

Coxiella burnetii is the etiologic agent of Q fever, a worldwide zoonosis. Cattle, sheep and goats are considered the main reservoirs of the disease. Transmission to humans occurs mainly through the inhalation of infectious aerosols from milk, faeces, urine, and birth products from infected ruminants. In this study, a 2-year longitudinal approach was performed to ascertain the excretion of C. burnetii in bulk t...


Serological evidence of West Nile Virus infection in horses from the municipali...

Loureiro, Filipa; Pires, Humberto; Cardoso, Luis; Lopes, Ana Patrícia; Fontes, Maria da Conceição; Santos Pintado, Cristina Maria Baptista

West Nile Virus (WNV) is an RNA virus from the family Flaviviridae. It is transmitted by several genera of mosquitoes, with Cullex spp. as the main vectors identified in Europe and North America. Birds are amplifying agents and important to the transmission cycle, during the viremia period. Equines are considered dead-ends hosts and are recognized as sentinels of the virus in many countries.


Ehrlichia canis and Rickettsia conorii Infections in Shelter Dogs: Seropositivi...

Afonso, Paulo; Lopes, Ana Patrícia; Quintas, Helder; Cardoso, Luís Miguel; Coelho, Ana Cláudia

A cross-sectional study was conducted to gain insight into the epidemiology of canine ehrlichiosis and rickettsiosis in northern Portugal. Specific IgG antibodies to Ehrlichia canis were analysed using a commercial enzyme-linked immunosorbent assay (ELISA), and antibodies to Rickettsia conorii were analysed using a commercial indirect immunofluorescence antibody test (IFAT). A total of 113 dogs from two differe...

Date: 2024   |   Origin: Biblioteca Digital do IPB

Mitochondrial metabolism drives low-density lipoprotein-induced breast cancer c...

Nóbrega-Pereira, Sandrina; Santos, Francisco; Santos, Miguel Oliveira; Serafim, Teresa L.; Lopes, Ana Patrícia; Coutinho, Diogo; Carvalho, Filipa S.

Most cancer-related deaths are due to metastases. Systemic factors, such as lipid-enriched environments [as low-density lipoprotein (LDL)-cholesterol], favor breast cancer, including triple-negative breast cancer (TNBC) metastasis formation. Mitochondria metabolism impacts TNBC invasive behavior but its involvement in a lipid-enriched setting is undisclosed. Here we show that LDL increases lipid droplets, induc...


Seropositivity for Coxiella burnetii in wild boar (Sus scrofa) and red deer (Ce...

Pires, Humberto; Cardoso, Luís; Lopes, Ana Patrícia; Fontes, Maria da Conceição; Matos, Manuela; Pintado, Cristina Santos; Figueira, Luís

Q fever is caused by the pathogen Coxiella burnetii and is a zoonosis that naturally infects goats, sheep, and cats, but can also infect humans, birds, reptiles, or arthropods. A survey was conducted for the detection of antibodies against C. burnetii in a sample of 617 free-ranging wild ruminants, 358 wild boar (Sus scrofa) and 259 red deer (Cervus elaphus), in east–central Portugal during the 2016–2022 huntin...


Prevalence and risk factors for hepatitis E virus in wild boar and red deer in ...

Pires, Humberto; Cardoso, Luís; Lopes, Ana Patrícia; Fontes, Maria da Conceição; Silva, Sérgio Santos; Matos, Manuela; Pintado, Cristina Santos

Hepatitis E virus (HEV) is a zoonotic foodborne virus with an annual infection prevalence of 20 million human cases, which seriously affects public health and economic development in both developed and developing countries. To better understand the epidemiology of HEV in Central Portugal, a cross-sectional study was conducted from 2016 to 2023 with sera samples from wild ungulates. The seroprevalence and risk f...


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