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WIN55,212-2 induces caspase-independent apoptosis on human glioblastoma cells b...
Silva, Ana Gabriela; Lopes, Caio Fabio Baeta; Carvalho Júnior, Clóvis Gomes; Thomé, Ralph Gruppi; Santos, Hélio Batista dos; Reis, R. M.Despite the standard approaches to treat the highly aggressive and invasive glioblastoma (GBM), it remains incurable. In this sense, cannabinoids highlight as a promising tool, because this tumor overexpresses CB1 and/or CB2 receptors and being, therefore, can be susceptible to cannabinoids treatment. Thus, this work investigated the action of the cannabinoid agonist WIN55-212-2 on GBM cell lines and non-malign...
Date: 2019
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Origin: RepositóriUM - Universidade do Minho