6 documents found, page 1 of 1
A mathematical model of fibrinogen-mediated erythrocyte-erythrocyte adhesion
Lopes, Catarina S.; Curty, Juliana; Carvalho, Filomena A.; Hernández-Machado, A.; Kinoshita, Koji; Santos, Nuno C.; Travasso, Rui D. M.Erythrocytes are deformable cells that undergo progressive biophysical and biochemical changes affecting the normal blood flow. Fibrinogen, one of the most abundant plasma proteins, is a primary determinant for changes in haemorheological properties, and a major independent risk factor for cardiovascular diseases. In this study, the adhesion between human erythrocytes is measured by atomic force microscopy (AFM...
A mathematical model of fibrinogen-mediated erythrocyte–erythrocyte adhesion
Lopes, Catarina S.; Curty, Juliana; Carvalho, Filomena Almeida; Hernández-Machado, A.; Kinoshita, Koji; Santos, Nuno C.; Travasso, Rui D. M.Erythrocytes are deformable cells that undergo progressive biophysical and biochemical changes affecting the normal blood flow. Fibrinogen, one of the most abundant plasma proteins, is a primary determinant for changes in haemorheological properties, and a major independent risk factor for cardiovascular diseases. In this study, the adhesion between human erythrocytes is measured by atomic force microscopy (AFM...
Cholesteryl hemiazelate causes lysosome dysfunction impacting vascular smooth m...
Alves, Liliana S.; Marques, André R. A.; Padrão, Nuno; Carvalho, Filomena A.; Ramalho, José; Lopes, Catarina S.; Soares, Maria I. L.; Futter, Clare E.In atherosclerotic lesions, vascular smooth muscle cells (VSMCs) represent half of the foam cell population, which is characterized by an aberrant accumulation of undigested lipids within lysosomes. Loss of lysosome function impacts VSMC homeostasis and disease progression. Understanding the molecular mechanisms underlying lysosome dysfunction in these cells is, therefore, crucial. We identify cholesteryl hemia...
Fatty acids composition in yellow-legged (Larus michahellis) and lesser black-b...
Lopes, Catarina S.; Antunes, Raquel C. C.; Paiva, Vitor H.; Goncalves, Ana M. M.; Correia, Jorge Manuel de Jesus; Ramos, Jaime A.Urban habitats offer spatially and temporally predictable anthropogenic food sources for opportunistic species, such as several species of gulls that are known to exploit urban areas and take advantage of accessible and diverse food sources, reducing foraging time and energy expenditure. However, human-derived food may have a poorer nutritional quality than the typical natural food resources and foraging in urb...
Molecular biomarkers associated with respiratory insufficiency in amyotrophic l...
Pronto-Laborinho, Ana Catarina; Lopes, Catarina S.; Santos, Nuno C.; Carvalho, Filomena A.; Carvalho, Mamede de
Atomic force microscopy : a tool for imaging, manipulating biomolecules, and qu...
Lopes, Catarina S.; Carvalho, Carvalho; Santos, Nuno C.