Background: Immunological protection via breastfeeding is well known. The immunological profile of human milk changes during lactation. No clinical trials have been conducted in lactating women with the newest mRNA vaccines against SARS- CoV-2. A Few studies have shown the presence of antibodies in breastmilk after vaccination. The aim of this work is to study possible antibodies transfer via breastmilk and als...
The "tubulin code" combines different a/ß-tubulin isotypes with several post-translational modifications (PTMs) to generate microtubule diversity in cells. During cell division, specific microtubule populations in the mitotic spindle are differentially modified, but only recently, the functional significance of the tubulin code, with particular emphasis on the role specified by tubulin PTMs, started to be eluci...
This study examined the developmental trajectories of general and breathing movements in fetal twins. Fetal movement patterns were assessed from real-time ultrasound recordings performed at 12-15, 20-23, and 28-32 weeks of gestation in 42 twin pairs. Results indicated that both general movements and breathing movements followed a curvilinear, inverted U-shaped curve. Developmental trajectories were unrelated wi...
Visual quality of volume rendering for medical imagery strongly depends on the underlying transfer function. Conventional Windows–Icons–Menus–Pointer interfaces typically refer the user to browse a lengthy catalog of predefined transfer functions or to pain-staking refine the transfer function by clicking and dragging several independent handles. To turn the standard design process less difficult and tedious, t...
Atypical haemolytic uraemic syndrome (aHUS) is a rare, life-threatening, chronic, genetic disease due to uncontrolled alternative pathway complement activation. In this report, we discuss the case of a heterozygous carrier of a mutation on both factor H and membrane cofactor protein, who persistently presents haemolytic anaemia without need for blood transfusions, normal platelet count, normal renal function an...
Quantifying the impact of air pollution on the publics health has become an increasingly critical component in policy discussion. Recent data indicate that more than 70% of the world population lives in cities. Several studies reported that current levels of air pollutants in urban areas are associated with adverse health risks, namely, cardiovascular diseases and lung cancer. IARC recently classified outdoor a...
Malaria is one of the most important infectious diseases in underdeveloped countries, particularly in Africa. [1, 2, 3] It affects about 500 million people each year, leading to 1.5 million deaths per year. [2, 3] Multi-resistance to most antimalarials in use is now wide spread, while the cost of effective treatment, through different antimalarial drug combinations, is prohibitive for the majority of the affect...
Malaria a serious parasitic disease, spread by mosquitoes from Anopheles species, is still the most devastating in the world. It has been estimated that in the last 20 years mortality from malaria has doubled (it is currently 3 millions deaths annually), and a major factor responsible for this increase is the resistance of malaria parasites to antimalarial drugs.1 Consequently, there is an urgent need to discov...
Infectious diseases caused by bacteria, fungi, viruses and parasites are a major threat to public health, despite great progress in therapy. The impact of infectious diseases is especially important in developing countries, where drugs are limited and the emergence of widespread drug resistance is a reality.1 Malaria is a major parasitic disease in the tropical and subtropical regions of the world. It is respon...