23 documents found, page 1 of 3

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Prognosis of Nonagenarian ICU Patients A Bayesian analysis of prospective Europ...

Dankl, Daniel; Bruno, Raphael Romano; Beil, Michael; Flaatten, Hans; Kelm, Malte; Sigal, Sviri; Szczeklik, Wojciech; Elhadi, Muhammed

Publisher Copyright: © The Author(s) 2025.; Background: As the population ages, the number of very elderly patients (≥ 90 years, nonagenarians) admitted to intensive care units (ICUs) is increasing. This trend raises concerns about the appropriateness of ICU care for this age group, especially due to the uncertainty surrounding their prognosis. Some studies suggest that elderly ICU patients have outcomes simila...


The association of premorbid conditions with 6-month mortality in acutely admit...

de Lange, Dylan W; Soliman, Ivo W; Leaver, Susannah; Boumendil, Ariane; Haas, Lenneke E M; Watson, Ximena; Boulanger, Carol; Szczeklik, Wojciech

© 2024. The Author(s).; BACKGROUND: Premorbid conditions influence the outcome of acutely ill adult patients aged 80 years and over who are admitted to the ICU. The aim of this study was to determine the influence of such premorbid conditions on 6 month survival. METHODS: Prospective cohort study in 242 ICUs from 22 countries including patients 80 years or above, admitted over a 6 months period to an ICU betwee...


In reply

Wolff, Georg; Wernly, Bernhard; Flaatten, Hans; Fjølner, Jesper; Bruno, Raphael Romano; Artigas, Antonio; Pinto, Bernardo Bollen; Schefold, Joerg C.


Reporting SOFA in research

Putowski, Zbigniew; Czok, Marcelina; Polok, Kamil; Guidet, Bertrand; Jung, Christian; Bruno, Raphael Romano; de Lange, Dylan; Leaver, Susannah

Publisher Copyright: © 2023 Via Medica. All rights reserved.; Background: The Sequential Organ Failure Assessment (SOFA) score is the sum of 6 components, each representing one organ system with dysfunction classified on a 4-point scale. In research, usually by default, the total SOFA score is taken into account, but it may not reflect the severity of the condition of the individual organs. Often, these values ...


Frailty’s influence on 30-day mortality in old critically ill ICU patients

Wernly, Bernhard; Bruno, Raphael Romano; Beil, Michael; Flaatten, Hans; Kelm, Malte; Sigal, Sviri; Szczeklik, Wojciech; Elhadi, Muhammed

Funding Information: We acknowledge all members of the VIP community. Publisher Copyright: © 2023, The Author(s).; Introduction: Frailty is widely acknowledged as influencing health outcomes among critically ill old patients. Yet, the traditional understanding of its impact has predominantly been through frequentist statistics. We endeavored to explore this association using Bayesian statistics aiming to provid...


Outcomes of patients aged ≥80 years with respiratory failure initially treated ...

Polok, Kamil; Fronczek, Jakub; Guidet, Bertrand; Artigas, Antonio; De Lange, Dylan W.; Fjølner, Jesper; Leaver, Susannah; Beil, Michael; Sviri, Sigal

Background: Non-invasive ventilation (NIV) has been commonly used to treat acute respiratory failure due to COVID-19. In this study we aimed to compare outcomes of older critically ill patients treated with NIV before and during the COVID-19 pandemic. Methods: We analysed a merged cohort of older adults admitted to intensive care units (ICUs) due to respiratory failure. Patients were enrolled into one of two pr...


Health-related quality of life in older patients surviving ICU treatment for CO...

Soliman, Ivo W; Leaver, Susannah; Flaatten, Hans; Fjølner, Jesper; Wernly, Bernhard; Bruno, Raphael R; Artigas, Antonio; Bollen Pinto, Bernardo

Funding: In addition, the study was supported by a grant from the European Open Science Cloud (EOSC). EOSCsecretariat.eu has received funding from the European Union’s Horizon Programme call H2020-INFRAEOSC-05-2018-2019, grant agreement number 831644. This work was supported by the Forschungskommission of the Medical Faculty of the Heinrich-Heine-University Düsseldorf, No. 2018-32 to G.W. and No. 2020-21 to R.R...


Association of chronic heart failure with mortality in old intensive care patie...

Bruno, Raphael Romano; Wernly, Bernhard; Wolff, Georg; Fjølner, Jesper; Artigas, Antonio; Bollen Pinto, Bernardo; Schefold, Joerg C

Funding: This study was endorsed by the ESICM. Free support for running the electronic database was granted from the Department of Epidemiology, Aarhus University, Denmark. The support of the study in France by a grant from ‘Fondation Assistance Publique-Hôpitaux de Paris pour la recherche’ is greatly appreciated. In Norway, the study was supported by a grant from the Health Region West. In addition, the study ...


The association of the Activities of Daily Living and the outcome of old intens...

Bruno, Raphael Romano; Wernly, Bernhard; Flaatten, Hans; Fjølner, Jesper; Artigas, Antonio; Baldia, Philipp Heinrich; Binneboessel, Stephan

Open Access funding enabled and organized by Projekt DEAL. This study was endorsed by the ESICM. Free support for running the electronic database and was granted from the dep. of Epidemiology, University of Aarhus, Denmark. Bruno et al. Annals of Intensive Care (2022) 12:26 Page 10 of 11 The support of the study in France by a grant from Fondation Assistance Publique-Hôpitaux de Paris pour la recherche is great...


Disease-course adapting machine learning prognostication models in critically i...

Jung, Christian; Mamandipoor, Behrooz; Fjølner, Jesper; Bruno, Raphael; Wernly, Bernhard; Artigas, Antonio; Bollen Pinto, Bernardo; Schefold, Joerg C

Funding: he support of the study in France by a grant from Fondation Assistance Publique-Hôpitaux de Paris Pour la Recherche is greatly appreciated. In Norway, the study was supported by a grant from Health Region West. In addition, EOSCsecretariat.eu provided support and has received funding from the European Union’s Horizon Programme call H2020-INFRAEOSC-05-2018-2019, grant agreement number 831644. This work ...


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