9 documents found, page 1 of 1
Single nucleotide polymorphisms affect miRNA target prediction in bovine
de Sousa, Marco Antônio Perpétuo [UNESP]; de Athayde, Flavia Regina Florêncio [UNESP]; Maldonado, Mariângela Bueno Cordeiro [UNESP]Made available in DSpace on 2021-06-25T10:28:32Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-04-01; Single nucleotide polymorphisms (SNPs) can have significant effects on phenotypic characteristics in cattle. MicroRNAs (miRNAs) are small, non-coding RNAs that act as post-transcriptional regulators by binding them to target mRNAs. In the present study, we scanned ~56 million SNPs against 1,064 bovine m...
Vitamin B-12 is neuroprotective in experimental pneumococcal meningitis through...
Queiroz, Karina Barbosa de; Cavalcante-Silva, Vanessa; Lopes, Flavia Lombardi [UNESP]; Rocha, Gifone Aguiar; D'Almeida, Vania; Coimbra, Roney SantosMade available in DSpace on 2020-12-10T20:13:47Z (GMT). No. of bitstreams: 0 Previous issue date: 2020-04-01; Inova Fundacao Oswaldo Cruz (FIOCRUZ); Background Bacterial meningitis (BM) causes apoptotic damage to the hippocampus and homocysteine (Hcy) accumulation to neurotoxic levels in the cerebrospinal fluid of children. The Hcy pathway controls bioavailability of methyl, and its homeostasis can be modulated...
Gene expression is associated with virulence in murine macrophages infected wit...
de Araújo, Erivelto Corrêa [UNESP]; Garcia, Leandro Encarnação [UNESP]; Araújo, Matheus Janeck [UNESP]; Oliveira-Junior, Itamar SouzaMade available in DSpace on 2020-12-12T02:31:03Z (GMT). No. of bitstreams: 0 Previous issue date: 2019-12-01; Leptospira genus contains species that affect human health with varying degrees of pathogenicity. In this context, we aimed to evaluate the differences in the modulation of host gene expression by strains of Leptospira varying in virulence. Our data showed a high number of differentially expressed trans...
Association of Copy Number Variation at Intron 3 of HMGA2 With Navel Length in ...
Aguiar, Tamiris Sayuri [UNESP]; Pintor Torrecilha, Rafaela Beatriz [UNESP]; Milanesi, Marco [UNESP]; Harth Utsunomiya, Adam Taiti [UNESP]Made available in DSpace on 2019-10-04T12:33:28Z (GMT). No. of bitstreams: 0 Previous issue date: 2018-12-07; Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq); Navel injuries caused by friction against the pasture can promote infection, reproductive problems and costly treatments in beef cattle raised in extensive systems. A hapl...
Relationship of peripheral blood mononuclear cells miRNA expression and parasit...
Bragato, Jaqueline Poleto [UNESP]; Melo, Larissa Martins [UNESP]; Venturin, Gabriela Lovizutto [UNESP]; Rebech, Gabriela Torres [UNESP]Made available in DSpace on 2019-10-06T15:26:57Z (GMT). No. of bitstreams: 0 Previous issue date: 2018-12-01; Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); Visceral leishmaniasis (VL) in humans is a chronic and often fatal disease if left untreated. Dogs appear to be the main reservoir host for L. infantum infection, however, in many regions other canids such as jackals, foxes, wolves and other...
Transcriptome datasets of macrophages infected with different strains of Leptos...
de Araújo Junior, Erivelto Corrêa [UNESP]; Garcia, Leandro Encarnação [UNESP]; Melo, Larissa Martins [UNESP]; Bragato, Jaqueline Poleto [UNESP]Made available in DSpace on 2018-12-11T17:35:20Z (GMT). No. of bitstreams: 0 Previous issue date: 2018-02-01; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES); Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); The datasets reported herein provide information about microarray experiment of macrophage cell line J774A.1 infected with three different strains of Leptospira spp. Transc...
Characterization of the microtranscriptome of macrophages infected with virulen...
Garcia, Leandro Encarnação [UNESP]; de Araújo Junior, Erivelto Corrêa [UNESP]; Melo, Larissa Martins [UNESP]; Bragato, Jaqueline Poleto [UNESP]Made available in DSpace on 2018-12-11T17:37:52Z (GMT). No. of bitstreams: 0 Previous issue date: 2018-07-06; Leptospirosis is a bacterial zoonosis, caused by Leptospira spp., that leads to significant morbidity and mortality worldwide. Despite considerable advances, much is yet to be discovered about disease pathogenicity. The influence of epigenetic mechanisms, particularly RNA-mediated post-transcriptional r...
Data on differentially expressed miRNAs in dogs infected with Leishmania infantum
Bragato, Jaqueline Poleto [UNESP]; Melo, Larissa Martins [UNESP]; Venturin, Gabriela Lovizutto [UNESP]; Rebech, Gabriela Torres [UNESP]Made available in DSpace on 2018-12-11T16:51:46Z (GMT). No. of bitstreams: 0 Previous issue date: 2018-04-01; Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); This paper contains data on differentially expressed miRNAs in peripheral blood mononuclear cells (PBMC) of dogs naturally infected by Leishmania (L.) infantum compared to healthy dogs. In recent years, studies with miRNAs have shown that th...
Chromatin modifying agents in the in vitro production of bovine embryos
Monteiro, Fabio Morato [UNESP]; Oliveira, Clara Slade [UNESP]; Oliveira, Letícia Zoccolaro [UNESP]; Saraiva, Naiara Zoccal [UNESP]Submitted by Vitor Silverio Rodrigues (vitorsrodrigues@reitoria.unesp.br) on 2014-05-27T11:26:16Z No. of bitstreams: 0Bitstream added on 2014-05-27T14:31:24Z : No. of bitstreams: 1 2-s2.0-79958143070.pdf: 1200575 bytes, checksum: e9a2a647484ef703e41f04a0d669cf95 (MD5); Made available in DSpace on 2014-05-27T11:26:16Z (GMT). No. of bitstreams: 0 Previous issue date: 2011-12-01; The low efficiency observed in clo...