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Tackling water contamination by oncologic drugs: Supported ionic liquids as sus...

Francisco, R; Monteiro, B; Santos, MJ; e Silva, FA; Venâncio, C; Neves, MC; Lopes, I; Sousa, Ana Catarina

Due to the increasing incidence of cancer, the consumption of highly toxic oncological drugs is continuously growing. Given the current lack of efficient technologies to remove/treat these toxic drugs in wastewater treatment plants, the environmental quality is compromised, and aquatic organisms are at risk. To address this critical environmental burden, a new strategy based on supported ionic liquids (SILs) fo...


Scaling-Up Digital Follow-Up Care Services: Collaborative Development and Imple...

Azevedo, S; Guede-Fernández, F; Hafe, F; Dias, P; Lopes, I; Cardoso, N; Coelho, P; Santos, J; Fragata, J; Vital, C; Semedo, H; Gualdino, A; Londral, A

Background: COVID-19 increased the demand for Remote Patient Monitoring (RPM) services as a rapid solution for safe patient follow-up in a lockdown context. Time and resource constraints resulted in unplanned scaled-up RPM pilot initiatives posing risks to the access and quality of care. Scalability and rapid implementation of RPM services require social change and active collaboration between stakeholders. The...


Monitoring Adherence to Asthma Inhalers Using the InspirerMundi App: Analysis o...

Jácome, C; Almeida, R; Pereira, AM; Amaral, R; Vieira-Marques, P; Mendes, S; Alves-Correia, M; Ferreira, JA; Lopes, I; Gomes, J; Araújo, L; Couto, M

Background: Poor medication adherence is a major challenge in asthma and objective assessment of inhaler adherence is needed. InspirerMundi app aims to monitor inhaler adherence while turning it into a positive experience through gamification and social support. Objective: We assessed the medium-term feasibility of the InspirerMundi app to monitor inhaler adherence in real-world patients with persistent asthma ...


Validation of App and Phone Versions of the Control of Allergic Rhinitis and As...

Jácome, C; Pereira, AM; Almeida, R; Amaral, R; Correia, MA; Mendes, S; Vieira-Marques, P; Ferreira, JA; Lopes, I; Gomes, J; Vidal, C; López Freire, S


Gold nanorods induce early embryonic developmental delay and lethality in zebra...

Mesquita, B; Lopes, I; Silva, S; Bessa, MJ; Starykevich, M; Carneiro, J; Galvão, LP; Ferreira, MGS; Tedim, J; Teixeira, JP; Fraga, S

Due to their unique electronic and optical features, gold nanoparticles (AuNP) have received a great deal of attention for application in different fields such as catalysis, electronics, and biomedicine. The large-volume manufacturing predicted for future decades and the inevitable release of these substances into the environment necessitated an assessment of potential adverse human and ecological risks due to ...


Can serum angiogenin be used to improve the diagnostic performance in prostate ...

Pina, F; Botelho, F; Lopes, T; Lopes, I; Figueiredo, G; Portugal, R; Ferro, A; Cruz, F; Barros, H; Lunet, N

Several biomarkers have been studied to avoid unnecessary biopsies resulting from suboptimal performance of prostate-specific antigen (PSA) testing. We aimed to assess the use of serum angiogenin as a prostate cancer diagnostic tool among candidates for biopsy. We selected 252 patients referred for ultrasound-guided transrectal prostate biopsy on the basis of an abnormal digital rectal examination and/or elevat...


Solar Constraints on Asymmetric Dark Matter

Lopes, I; Silk, J

The dark matter content of the universe is likely to be a mixture of matter and antimatter, perhaps comparable to the measured asymmetric mixture of baryons and antibaryons. During the early stages of the universe, the dark matter particles are produced in a process similar to baryogenesis, and dark matter freezeout depends on the dark matter asymmetry and the annihilation cross section (s-wave and p-wave annih...


Solar Neutrino Physics: Sensitivity to Light Dark Matter Particles

Lopes, I; Silk, J

Neutrinos are produced in several neutrino nuclear reactions of the proton-proton chain and carbon-nitrogen-oxygen cycle that take place at different radii of the Sun's core. Hence, measurements of solar neutrino fluxes provide a precise determination of the local temperature. The accumulation of non-annihilating light dark matter particles (with masses between 5 GeV and 16 GeV) in the Sun produces a change in ...


Effects of cyclic fluctuations in meridional circulation using a low-order dyna...

Lopes, I; Passos, D

We develop and subsequently explore the solution space of a simple flux transport dynamo model that incorporates a time-dependent large-scale meridional circulation. Based on recent observations, we prescribed an analytical form for the amplitude of this circulation and study its impact in the evolution of the magnetic field. We find that cyclic variations in the amplitude and frequency of the meridional flow a...


Impact of a Realistic Density Stratification on a Simple Solar Dynamo Calculation

Lopes, I; Cardoso, E

In our Sun, the magnetic cycle is driven by the dynamo action occurring inside the convection zone, beneath the surface. Rotation couples with plasma turbulent motions to produce organized magnetic fields that erupt at the surface and undergo relatively regular cycles of polarity reversal. Among others, the axisymmetric dynamo models have been proved to be a quite useful tool to understand the dynamical process...


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