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An overview of the therapeutic potential of dimeric flavonoids for targeting ca...
Lopes, Inês; Meireles, Isabel; Rocha, Rafaela; Medeiros, Rui; Cerqueira, FátimaEvidence found in the literature indicates that dimeric flavonoids constitute important therapeutic options against cancer. Using these molecules to prevent cancer progression might be a novel and promising therapeutic approach with advantages like fewer side effects, easy access in nature, overall health benefits and overcoming drug resistance. Cancer is a complex disease and still not understood, but there ar...
A gamified virtual reality exposure therapy for individuals with Arachnophobia:...
Lopes, Inês; Almeida, Raquel Simões de; Gomes, Paulo Veloso; Marques, António; Simões de Almeida, Raquel; Machado Veloso Gomes, Paulo SérgioArachnophobia is a specific phobia characterized by an intense and persistent fear of spiders, often leading to avoidance behaviors that can significantly impact daily life. Virtual Reality Exposure Therapy (VRET) offers a controlled, adaptable, and immersive therapeutic environment, allowing for greater personalization, flexibility, and the real-time modulation of exposure parameters. This pilot study employed...
The artificial doctor : consumer perception on AI-driven preliminary medical di...
Lopes, InêsArtificial Intelligence (AI) has emerged as a powerful tool capable of transforming industries. The healthcare industry hopes to leverage this technology to reduce costs, improve patient care, medical diagnosis and treatment recommendations, administrative work, and so forth. While there is optimism, skepticism about this technology still causes consumers to resist adopting it, which in turn can prevent the ind...
Virtual reality exposure therapy for Arachnophobia: A pilot study
Lopes, Inês; Almeida, Raquel Simões de; Gomes, Paulo Veloso; Sá, Vítor J.; Oliveira, Gonçalo; Marques, António; Machado Veloso Gomes, Paulo SérgioArachnophobia is a chronic disorder leading to significant avoidance of spider-related situations. This pilot study examines the effectiveness of Virtual Reality Exposure Therapy (VRET) for treating arachnophobia. The study included 25 participants who completed fear questionnaires and avoidance tests before, after and two weeks after the intervention. The intervention consisted of a session of progressive expo...
A cyclam salt as an antifungal agent: Interference with Candida spp. and Crypto...
Cerqueira, Fátima; Medeiros, Rui; Lopes, Inês; Campos, Carla; Ferraz, Maria Pia; Silva, Fernando; Alves, Luís G.; Pinto, EugéniaThe importance of fungal infections, particularly those caused by yeasts, is increasing among the medical community. Candida albicans and Cryptococcus neoformans are amongst the high-priority fungal species identified by the World Health Organization (WHO) and are considered in the critical group, while Candida krusei is included in the medium-priority group. The cyclam salt H4[H2(4-CF3PhCH2)2Cyclam]Cl4 proved ...
Disclosing the antifungal mechanisms of the Cyclam Salt H4[H2(4-CF3PhCH2)2Cycla...
Costa, Inês; Lopes, Inês; Morais, Mariana; Silva, Renata; Remião, Fernando; Medeiros, Rui; Alves, Luís G.; Pinto, Eugénia; Cerqueira, FátimaMycoses are one of the major causes of morbidity/mortality among immunocompromised individuals. Considering the importance of these infections, the World Health Organization (WHO) defined a priority list of fungi for health in 2022 that include Candida albicans as belonging to the critical priority group and Pichia kudriavzevii (Candida krusei) to the medium priority group. The existence of few available antifu...
Guia de Boas Práticas para a manutenção de Faixas de Gestão de Combustível
Folgôa Batista, Maria Teresa; Moreira, André; Afonso, José; Lopes, Inês; Querido, Cassandra; Freire, António; Marques, Pedro; Rocha, IsildaA preservação da Floresta, ao nível dos ecossistemas e dos recursos existentes, passa pela construção de uma estratégia de defesa contra os incêndios, aliada à proteção das espécies, respeitando a biodiversidade da região onde se executa a gestão de combustível, não obstante o cumprimento da legislação que define os critérios para a execução das faixas de gestão de combustível.Neste sentido, este manuel pretend...
Relatório de Estágio Curricular – COFICAB Portugal (Guarda)
Lopes, InêsA influência da comunicação interna nas organizações é considerada essencial para o sucesso e fortalecimento do relacionamento entre a própria organização e os seus funcionários e esta comunicação deve ser estratégica e decisiva, centrando-se sempre no envolvimento dos funcionários. O presente relatório tem como objetivo apresentar as aprendizagens mais relevantes durante o estágio efetuado na empresa COFICAB, ...
Antimicrobial activity of dimeric flavonoids
Lopes, Inês; Campos, Carla; Medeiros, Rui; Cerqueira, FátimaDistributed throughout the environment are various microorganisms such as bacteria, fungi, parasites, and viruses. Although many are part of the human microbiome, many are pathogenic and cause infections ranging from mild to severe. In recent years, the identification of multidrug-resistant microorganisms has become a serious public health problem. The resulting infections call into question the therapeutic cap...
Impact of a virtual reality-based simulation on empathy and knowledge toward Mi...
Lopes, Inês; Simões De Almeida, Raquel; Marques, AntónioVirtual Reality (VR) is considered a powerful resource for developing empathy and pro-social behaviors since it allows individuals to experience a situation that is close to reality from another person's perspective. This quasi-experimental study was designed to measure the impact that a VR simulation which mimics the experience of misophonic symptoms, while performing a cognitive task, has on empathy and knowl...