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Ascorbic Acid Chemosensitizes Colorectal Cancer Cells and Synergistically Inhib...

Pires, Ana S.; Marques, Cláudia R.; Encarnação, João C.; Abrantes, Ana M.; Marques, Inês A.; Laranjo, Mafalda; Oliveira, Rui; Lopes, João E. Casalta

Colorectal cancer (CRC) is continuously classified as one of the most incidental and mortal types of cancer worldwide. The positive outcomes of the conventional chemotherapy are frequently associated with high toxicity, which often leads to the suspension of the treatment. Growing evidences consider the use of pharmacological concentrations of ascorbic acid (AA), better known as vitamin C, in the treatment of c...

Date: 2018   |   Origin: Estudo Geral - Universidade de Coimbra
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