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Economic burden of Parkinson’s disease : a multinational, real-world, cost-of-i...
Chaudhuri, K. Ray; Azulay, Jean-Philippe; Odin, Per; Lindvall, Susanna; Domingos, Josefa; Alobaidi, Ali; Kandukuri, Prasanna L.; Chaudhari, Vivek S.Background: Parkinson’s disease is now one of the fastest-growing neurodegenerative disorders in the developed world, with an increasing prevalence and associated socioeconomic costs. Progression of the disease leads to a gradual deterioration in patients’ quality of life, despite optimal treatment, and both medical and societal needs increase, often with the assistance of paid and/or unpaid caregivers. Objecti...
Psychometric properties of clinical indicators for identification and managemen...
Antonini, Angelo; Pahwa, Rajesh; Odin, Per; Henriksen, Tove; Soileau, Michael J.; Rodriguez-Cruz, Ramon; Isaacson, Stuart H.; Merola, AristideIntroduction: Standardized and validated criteria to define advanced Parkinson’s disease (PD) or identify patient eligibility for device-aided therapy are needed. This study assessed the psychometric properties of clinical indicators of advanced PD and eligibility for device-aided therapy in a large population. Methods: This retrospective analysis of the Adelphi Parkinson’s Disease Specific Programme collected ...
Does the 5–2-1 criteria identify patients with advanced Parkinson's disease? Re...
Malaty, Irene A.; Martinez-Martin, Pablo; Chaudhuri, K. Ray; Odin, Per; Skorvanek, Matej; Jimenez-Shahed, Joohi; Soileau, Michael J.; Lindvall, SusannaBackground: The burden of Parkinson’s disease (PD) worsens with disease progression. However, the lack of objective and uniform disease classification challenges our understanding of the incremental burden in patients with advanced Parkinson’s disease (APD) and suboptimal medication control. The 5–2-1 criteria was proposed by clinical consensus to identify patients with advancing PD. Our objective was to evalua...