2 documents found, page 1 of 1
Systematic survey of randomized trials evaluating the impact of alternative dia...
El Dib, Regina [UNESP]; Tikkinen, Kari A.O.; Akl, Elie A.; Gomaa, Huda A.; Mustafa, Reem A.; Agarwal, Arnav; Carpenter, Christopher R.; Zhang, YuchenMade available in DSpace on 2018-12-11T17:09:38Z (GMT). No. of bitstreams: 0 Previous issue date: 2017-04-01; Objectives To provide a perspective on the current practice of randomized clinical trials (RCTs) of diagnostic strategies focusing on patient-important outcomes. Study Design and Setting We conducted a comprehensive search of MEDLINE and included RCTs published in full-text reports that evaluated altern...
Pharmacological characterization of Solanum cernuum Vell.: 31-norcycloartanones...
Lopes, Luciane C.; Carvalho, João E.; Kakimore, Marise; Vendramini-Costa, Débora B.; Medeiros, Maria Augusta; Spindola, Humberto M.; Ávila-Román, J.Cycloeucalenone (1) and 24-oxo-31-norcycloartanone (2) obtained from Solanum cernuum Vell. were assayed to explore their pharmacologic roles. Previous studies showed that (2) has selective activity against lung tumor cell line (NCIH460) which expresses high levels of COX-2, suggesting its role in inflammatory process, and also a link between chronic inflammation and cancer-associated process. Dichloromethane cr...