10 documents found, page 1 of 1

The SARS-CoV-2 Infection Among Students in the University of Porto: A Cross-Sec...

Objective: We aimed to quantify SARS-CoV-2 specific antibodies’ seroprevalence among university students in Porto. Methods: A rapid point of care testing for SARS-CoV-2 specific immunoglobulin (Ig) M and IgG antibodies was performed, and a questionnaire was applied to 6512 voluntary students from September to December 2020. We computed the apparent IgM, IgG, and IgM or IgG prevalence, and the true prevalence an...

Disclosing Azole Resistance Mechanisms in Resistant Candida Glabrata Strains En...

The pathogenic yeast Candida glabrata is intrinsically resilient to azoles and rapidly acquires resistance to these antifungals, in vitro and in vivo. In most cases azole-resistant C. glabrata clinical strains encode hyperactive CgPdr1 variants, however, resistant strains encoding wild-type CgPDR1 alleles have also been isolated, although remaining to be disclosed the underlying resistance mechanism. In this st...

Prevalence of SARS-CoV-2 antibodies among workers of the public higher educatio...

Objectives To assess the prevalence of SARS-CoV-2-specific IgM and IgG antibodies among workers of the three public higher education institutions of Porto, Portugal, up to July 2020. Methods A rapid point-of-care test for specific IgM and IgG antibodies of SARS-CoV-2 was offered to all workers (SD Biosensor STANDARD Q COVID-19 IgM/IgG Duo and STANDARD Q COVID-19 IgM/IgG Combo). Testing was performed and a quest...

Effect of denture-related stomatitis fluconazole treatment on oral Candida albi...

Denture-related stomatitis (DRS) is the most common condition affecting removable-denture wearers, and Candida albicans the most frequent pathogenic agent. Systemic antifungal treatment is indicated but recurrences are frequent. The aim of this study was to characterize the oral load, fluconazole susceptibility profile and genotypic variability of oral C. albicans isolates from patients with DRS before (T0), im...

Coreceptor Usage by HIV-1 and HIV-2 Primary Isolates: The Relevance of CCR8 Che...

The human immunodeficiency virus replication cycle begins by sequential interactions between viral envelope glycoproteins with CD4 molecule and a member of the seven-transmembrane, G-protein-coupled, receptors' family (coreceptor). In this report we focused on the contribution of CCR8 as alternative coreceptor for HIV-1 and HIV-2 isolates. We found that this coreceptor was efficiently used not only by HIV-2 but...

Value of morphotyping for the characterization of Candida albicans clinical iso...

Until recently, morphotyping, a method evaluating fringe and surface characteristics of streak colonies grown on malt agar has been recommended as a simple and unexpensive typing method for Candida albicans isolates. The discriminatory power and reproduci

Desenvolvimento de uma formulação com sais do ácido ascórbico-selecção de agent...

Nosocomial acquisition of yeasts

This report describes the nosocomial acquisition of Candida species by paediatric patients. Our findings suggest that the acquisition of C albicans was preferably endogenous, but some cases become from exogenous sources. Unlike other Candida species, C. p

Implication phospholipase, aspartyl proteinase and germ tube formation as virul...

Three different virulence factors were investigated in order to evaluate the pathogenicity of 150 yeasts isolates (75-C. albicans, 67-C. parapsilosis, 5-C. tropicalis, and 3 Saccharomyces cerevisiae). C. albicans isolates were the only that produced extra

Potential utility of random amplified polymorphic DNA (RAPD) and restriction en...

Two molecular methods were compared, random amplified polymorphic DNA (RAPD) and restriction endonuclease analysis (REA), in order to evaluate their ability to discriminate, and to characterize Madurella mycetomatis strains isolated from human mycetomas in different parts of the world. Both methods were able to cluster the Madurella mycetomatis isolates into the same number of distinct typing groups. However, R...