7 documents found, page 1 of 1
Anti-biofilm formulations, and uses thereof
Vaz, Irene Graça Azevedo Pina; Lopes, Maria Ascensão; Ferreira, Inês Ribeiro Valente Lucas; Henriques, Mariana; Rodrigues, Maria Elisa CostaAn anti-biofilm formulation for use in the treatment of infections comprising: methyl ethyl ketone and an organic co-solvent or an essential oil, wherein the anti-biofilm formulation is a biofilm disruptor.
Improvement of the efficacy of endodontic solvents by ultrasonic agitation
Ferreira, Inês; Braga, A. C.; Lopes, Maria Ascensão; Pina-Vaz, Irene[Excerpt] The success rates of endodontic treatment can reach levels from 86% to 98% (Abitbol et al., 2003). However, apical periodontitis may still persist or develop after treatment due to various factors, namely coronal leakage, caries or fractures, thus enabling reinfection by microorganisms of the oral cavity or proliferation of microorganisms in persisting endodontic infections (Siqueira, 2001, Correia-So...
Supplementary solvent irrigation efficacy on filling remnants removal comparing...
Ferreira, Inês; Babo, Pedro Miguel Sousa; Braga, A. C.; Lopes, Maria Ascensão; Gomes, Manuela E.; Pina-Vaz, IreneThis study aimed to compare the efcacy of XP-endo Finisher R and IrriSafe, with a solvent mixture of Methyl ethyl ketone/Tetrachloroethylene (MEK/TCE), in the removal of root flling residues. Twentyfour human mandibular incisors were pair-matched by micro-computed tomography according to volume and aspect ratio. After retreatment, specimens were allocated to two experimental groups (n= 12), according to the sup...
Adjunctive procedure with solvent mixtures in non-surgical endodontic retreatme...
Ferreira, Inês; Braga, A. C.; Lopes, Maria Ascensão; Pina-Vaz, IreneThe aim of this study was to compare the effects of new irrigation solvent mixtures with Methyl ethyl ketone (MEK)/Tetrachloroethylene (TCE) and MEK/Orange oil (OOil), and different agitation techniques on dentin hardness. One hundred forty-four mandibular teeth were prepared and standardized, with each root’s middle part transversely sectioned. Initial hardness was measured using a Vickers microhardness tester...
Efficacy and cytotoxicity of binary mixtures as root canal filling solvents
Ferreira, Inês; Grenho, Liliana; Gomes, Pedro; Braga, A. C.; Fernandes, Maria Helena; Lopes, Maria Ascensão; Pina-Vaz, IreneObjectives: This study reports the efficacy of two solvent mixtures on the dissolution of gutta-percha and AH Plus sealer, together with the cytotoxicity. Methods: Methyl ethyl ketone (MEK), orange oil, tetrachloroethylene, MEK/tetrachloroethylene (1:1), MEK/orange oil (1:1), and chloroform (control) were tested. Twelve groups (<i>n</i> = 15) of standardized stainless-steel molds filled with softened gutta-perc...
Long term performance evaluation of small-diameter vascular grafts based on pol...
Alexandre, Nuno; Amorim, Irina; Caseiro, Ana Rita; Pereira, Tiago; Alvites, Rui; Rêma, Alexandra; Gonçalves, Ana; Costa, Elisio; Santos-Silva, AliceThe functional and structural performance of a 5 cm synthetic small diameter vascular graft (SDVG) produced by the copolymerization of polyvinyl alcohol hydrogel with low molecular weight dextran (PVA/Dx graft) associated to mesenchymal stem cells (MSCs)-based therapies and anticoagulant treatment with heparin, clopidogrel and warfarin was tested using the ovine model during the healing period of 24 weeks. The ...
Application of artificial vascular polyvinyl alcohol hydrogel grafts in sheep -...
Alexandre, Nuno; Gärtner, Andrea; Amorim, Irina; Santos, José D.; Lopes, Maria Ascensão; Colette Maurício, Ana; Luís, Ana LúciaResearchers developed this project according with the tasks originally planned, so far focusing their research activities in the biocompatibility and functionality of vascular implants. The biocompatibility was studied by following the ISO standard 10993-6 for evaluation of medical devices through the evaluation and grading of inflammation caused by implants placed subcutaneously. The implants were placed in sh...