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Ridolfia segetum (L.) Moris (Apiaceae) from Portugal: A source of safe antioxid...

Cabral, C.; Poças Almeida, Juliana; Gonçalves, M.J.; Cavaleiro, C.; Cruz, M.T.; Salgueiro, L.

Ridolfia segetum (L.) Moris essential oil was obtained by hydrodistillation and analysed by GC and GC-MS. The antioxidant properties were evaluated through the TBARS assay, and the in vitro anti-inflammatory activity was assessed through inhibition of NO production triggered by the Toll-like receptor 4 (TLR4) agonist, lipopolysaccharide (LPS), in mouse macrophages. Assessment of cell viability was made through ...

Date: 2015   |   Origin: IC-online

Imunoterapia anti-tumoral com células dendríticas

Oliveira, T.G; Borges, O.; Cruz, M.T.

Dendritic cells (DCs) are professional antigen-presenting cells, which display an extraordinary capacity to induce and regulate T-cell responses. Because of their immunoregulatory capacities and because very small numbers of activated DCs are highly efficient in generating immune responses against antigens, DCs have been extensively used in clinical trials in order to elicit or amplify immune responses against ...

Date: 2013   |   Origin: Acta Farmacêutica Portuguesa

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