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Anticoagulation improves survival in patients with cirrhosis and portal vein th...

Guerrero, Antonio; Campo, Laura del; Piscaglia, Fabio; Scheiner, Bernhard; Han, Guohong; Violi, Francesco; Ferreira, Carlos; Téllez, Luis

Background & aims: Previous meta-analyses demonstrated the safety and efficacy of anticoagulation in the recanalization of portal vein thrombosis in patients with cirrhosis. Whether this benefit translates into improved survival is unknown. We conducted an individual patient data (IPD) meta-analysis to assess the effect of anticoagulation on all-cause mortality in patients with cirrhosis and portal vein thrombo...


Cirrhosis is associated with lower serological responses to COVID-19 vaccines i...

Simão, André; Palma, Carolina; Izquierdo-Sanchez, Laura; Putignano, Antonella; Carvalho-Gomes, Angela; Posch, Andreas; Zanaga, Paola; Girleanu, Irina

Background & aims: The response of patients with chronic liver disease (CLD) to COVID-19 vaccines remains unclear. Our aim was to assess the humoral immune response and efficacy of two-dose COVID-19 vaccines among patients with CLD of different aetiologies and disease stages. Methods: A total of 357 patients were recruited in clinical centres from six European countries, and 132 healthy volunteers served as con...


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