8 documents found, page 1 of 1
Weighted single-step GWAS and gene network analysis reveal new candidate genes ...
Marques, Daniele B. D.; Bastiaansen, John W. M.; Broekhuijse, Marleen L. W. J.; Lopes, Marcos S.; Knol, Egbert F.; Harlizius, BarbaraIn recent years, there has been increased interest in the study of the molecular processes that affect semen traits. In this study, our aim was to identify quantitative trait loci (QTL) regions associated with four semen traits (motility, progressive motility, number of sperm cells per ejaculate and total morphological defects) in two commercial pig lines (L1: Large White type and L2: Landrace type). Since the ...
Quantitative trait loci for carcass, internal organ and meat quality traits on ...
Paixão, Débora M.; Silva Filho, Miguel I. da; Pereira, Mário S.; Lopes, Marcos S.; Barbosa, Leandro; Souza, Katiene Régia Silva; Lopes, Paulo S.The objective of this study was to map quantitative trait loci (QTL) on porcine chromosomes 16, 17 and 18 and to determine their association with carcass, organ and meat quality traits. An F2 population was produced by crossing two boars of the naturalized Brazilian Piau breed with 18 commercial females (Landrace x Large White x Pietrain). The population was genotyped for 11 microsatellite markers distributed o...
Morphological and molecular differences in corpus luteum of pregnant sows from ...
Costa, Karine A.; Silva, Walmir da; Veroneze, Renata; Montes, José C.; Verardo, Lucas L.; Botelho, Margareth E.; Duarte, Marcio S.; Neves, Mariana M.Comprehending mechanisms controlling corpus luteum (CL) angiogenesis and apoptosis in pregnant sows is essential to understand the physiological role of these processes in CL function, progesterone production and consequently in conceptus development and prenatal mortality. CL from 54 sows from two genetic groups, a commercial line (COM) and the local Piau breed (LPB), were obtained for gene expression (n = 3 C...
Gene networks for total number born in pigs across divergent environments
Verardo, Lucas L.; Lopes, Marcos S.; Mathur, Pramod; Madsen, Ole; Silva1, Fabyano F.; Groenen, Martien A. M.; Knol, Egbert F.; Lopes, Paulo S.For reproductive traits such as total number born (TNB), variance due to different environments is highly relevant in animal breeding. In this study, we aimed to perform a gene-network analysis for TNB in pigs across different environments using genomic reaction norm models. Thus, based on relevant single-nucleotide polymorphisms and linkage disequilibrium blocks across environments obtained from GWAS, differen...
Use of multivariate analysis to evaluate genetic groups of pigs for dry-cured h...
Ventura, Henrique T.; Lopes, Paulo S.; Peloso, José V.; Guimarães, Simone E. F.; Carneiro, Antonio P. S.; Carneiro, Paulo L. S.Records of a pig population used for dry-cured ham production were used to evaluate genetic groups by multivariate analysis. The investigated genetic groups were as follows: DULL=Duroc×(Landrace×Large White), DULA=Duroc×Landrace, DUWI=Duroc×Large White, WIWI=Large White and DUDU=Duroc. Two groups were obtained for the carcass traits hot carcass weight (HCW), backfat thickness (BT) and loin depth (LD), with the ...
Fine mapping and single nucleotide polymorphism effects estimation on pig chrom...
Hidalgo, André M.; Lopes, Paulo S.; Paixão, Débora M.; Silva, Fabyano F.; Bastiaansen, John W.M.; Paiva, Samuel R.; Faria, Danielle A.Fine mapping of quantitative trait loci (QTL) from previous linkage studies was performed on pig chromosomes 1, 4, 7, 8, 17, and X which were known to harbor QTL. Traits were divided into: growth performance, carcass, internal organs, cut yields, and meat quality. Fifty families were used of a F2 population produced by crossing local Brazilian Piau boars with commercial sows. The linkage map consisted of 237 SN...
Revealing new candidate genes for reproductive traits in pigs: combining Bayesi...
Verardo, Lucas L.; Silva, Fabyano F.; Lopes, Marcos S.; Madsen, Ole; Bastiaansen, John W. M.; Knol, Egbert F.; Kelly, Mathew; Varona, LuisReproductive traits such as number of stillborn piglets (SB) and number of teats (NT) have been evaluated in many genome-wide association studies (GWAS). Most of these GWAS were performed under the assumption that these traits were normally distributed. However, both SB and NT are discrete (e.g. count) variables. Therefore, it is necessary to test for better fit of other appropriate statistical models based on ...
A canonical correlation analysis of the association between carcass and ham tra...
Ventura, Henrique T.; Lopes, Paulo S.; Peloso, José V.; Guimarães, Simone E.F.; Carneiro, Antonio Policarpo S.; Carneiro, Paulo L.S.The association between carcass and ham traits in a pig population used to produce dry-cured ham was studied using canonical correlation analysis. The carcass traits examined were hot carcass weight (HCW), backfat thickness (BT) and loin depth (LD), and the ham traits studied were gross ham weight (GHW), trimmed ham weight (THW), ham inner layer fat thickness (HIFT), ham outer layer fat thickness (HOFT), pH (pH...