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SIGAA: signaling automated analysis: a new tool for Ca2+ signaling quantificati...

Lopes, Rafael Faria; Gonçalves-Ribeiro, Joana; Sebastião, Ana M.; Meneses, Carlos; Vaz, Sandra H.

Astrocytes are non-neural cells, restricted to the brain and spinal cord, whose functions and morphology depend on their location. Astrocyte–astrocyte and astrocyte–neuron interactions occur through cytoplasmic Ca2+ level changes that are assessed to determine cell function and response (i.e., drug testing). The evaluation of alterations in intracellular Ca2+ levels primarily relies on fluorescence imaging tech...


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