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Biochemical imaging of normal, adenoma, and colorectal adenocarcinoma tissues b...

Piva,Juliana Aparecida de Almeida Chaves; Silva,João Lucas Rangel; Raniero,Leandro José; Lima,Carmen Silvia Passos; Arisawa,Emilia Angela Loschiavo

Introduction The colorectal cancer is a major health problem worldwide. Histology is considered the gold standard for differential diagnosis. However, it depends on the observer's experience, which can lead to discrepancies and poor results. Spectroscopic imaging by Fourier transform infrared (FTIR) is a technique that may be able to improve the diagnosis, because it is based on biochemical differences of the s...

Data: 2015   |   Origem: Oasisbr

Confocal Raman spectroscopy: determination of natural moisturizing factor profi...

Teixeira,Ana Paula; Rangel,João Lucas; Raniero,Leandro José; Tosato,Maira Gaspar; Fávero,Priscila Pereira; Martin,Airton Abrahão

INTRODUCTION: Skin health and skin care to reduce the effects of aging are the main interests of many researchers. The skin is very important because it protects the body from various effects of the external environment, and studies of the largest organ of the human body have been conducted since antiquity. In skin, aging effects are severe enough to promote changes in cell structure and biochemical composition...

Data: 2014   |   Origem: Oasisbr

FT-Raman spectroscopic study of skin wound healing in diabetic rats treated wit...

Coelho,Nayana Pinheiro Machado de Freitas; Raniero,Leandro; Costa,Charlytton Luís Sena da; Maia Filho,Antônio Luís Martins; Martins,Marcelino

INTRODUCTION: Patients with diabetes mellitus exhibit a delay in the lesion repair process. The active components of Cenostigma macrophyllum may represent a viable alternative to facilitate the recovery of these lesions. The aim of this study was to evaluate the effects of emulsion oil-water Cenostigma macrophyllum in the repair process of lesions in rats with induced diabetes. METHODS: 63 male rats (Wistar, 20...

Data: 2014   |   Origem: Oasisbr

Study of advanced rheumatoid arthritis

Carvalho,Carolina da Silva; Andrade,Luiz Eduardo Coelho; Keusseyan,Silene Peres; Rangel,João Lucas; Ferreira-Strixino,Juliana; Martin,Airton Abrahão

INTRODUCTION: Rheumatic diseases are considered public health problems affecting millions of people worldwide resulting in high and rising health-care costs. In this work, Fourier Transform Infrared spectroscopy associated to Partial Least Square regression (PLS) analysis was used to diagnose rheumatoid arthritis (RA) from human serum. METHODS: The sera of 94 individuals were collected, which included 47 from r...

Data: 2014   |   Origem: Oasisbr

Effects of various hydrogen peroxide bleaching concentrations and number of app...

Berger,Sandrine Bittencourt; Soares,Luis Eduardo Silva; Martin,Airton Abrahão; Ambrosano,Gláucia Maria Bovi; Tabchoury,Cínthia Pereira Machado

AIM: To evaluate the effects of three hydrogen peroxide (HP) concentrations on enamel mineral content (MC), following three peroxide applications and using three methods to measure the MC. METHODS : Forty samples were obtained from bovine incisors and randomly divided into 4 groups (n=10). The control group remained untreated, while the experimental groups were tested for three HP concentrations (10%, 35% and 5...

Data: 2014   |   Origem: Oasisbr

Evaluation of inorganic and organic bone components after application of an apa...

Maia Filho,Antonio Luiz Martins; Amaral,Fabrício Pires de Moura do; Martin,Airton Abrahão; Soares,Luís Eduardo Silva

The aim of this work was to study the influence of uncoated and apatite-coated Al2O3 implants on bone regeneration after 30 days of surgery in New Zealand white rabbits. Twelve samples of Al2O3 implants were prepared and half of them (n = 6) were apatite-coated by the modified biomimetic method. Three experimental groups were tested as Group C - control, surgery procedure without cerami c implant, Group Ce - un...

Data: 2014   |   Origem: Oasisbr

Análise da composição bioquímica da pele por espectroscopia Raman

Oliveira,Patrícia Karen; Tosato,Maira Gaspar; Alves,Rani de Souza; Martin,Airton Abrahão; Fávero,Priscila Pereira; Raniero,Leandro

O envelhecimento cutâneo caracteriza-se por alterações celulares e moleculares. Neste contexto, a espectroscopia Raman Confocal foi utilizada para medir estas alterações bioquímicas em função da profundidade da pele in vivo. Neste estudo houve a tentativa de correlacionar os modos vibracionais dos aminoácidos puros com os espectros da pele de voluntárias de diferentes faixas etárias. Foram coletados espectros i...

Data: 2012   |   Origem: Oasisbr

FT-Raman spectroscopy for the differentiation between cutaneous melanoma and pi...

Cartaxo,Sidney Bandeira; Santos,Ivan Dunshee de Abranches Oliveira; Bitar,Renata; Oliveira,Andréa Fernandes; Ferreira,Lydia Masako

Cutaneous melanoma is the most aggressive type of skin cancer and Ft-Raman spectroscopy has been studied as a potential method that could be a real alternative for early diagnosis of neoplasms. PURPOSE: To qualify the spectral FT-Raman data, in order to differentiate cutaneous melanoma and pigmented nevus. METHODS: For this study, 10 samples of cutaneous melanoma, 9 samples of pigmented nevi, and 10 samples of ...

Data: 2010   |   Origem: Oasisbr

Differential diagnosis in primary and metastatic cutaneous melanoma by FT-Raman...

Oliveira,Andrea Fernandes de; Santos,Ivan Dunshee de Abranches Oliveira; Cartaxo,Sidney Bandeira; Bitar,Renata Andrade

PURPOSE: To qualify the FT-Raman spectral data of primary and metastatic cutaneous melanoma in order to obtain a differential diagnosis. METHODS: Ten normal human skin samples without any clinical or histopathological alterations, ten cutaneous melanoma fragments, and nine lymph node metastasis samples were used; 105, 140 and 126 spectra were obtained respectively. Each sample was divided into 2 or 3 fragments ...

Data: 2010   |   Origem: Oasisbr

Influence of the photoinitiator system and light photoactivation units on the d...

Porto,Isabel Cristina Celerino de Moraes; Soares,Luis Eduardo Silva; Martin,Airton Abrahão; Cavalli,Vanessa; Liporoni,Priscila Christiane Suzy

The aim of this study was to observe the influence of two light polymerization units (LED or halogen light) on the degree of conversion (DC) of three dental composites with lighter shades and a different photoinitiator system. The top (T) and bottom (B) surfaces of 60 discs of composite resin (Filtek™ Supreme, Filtek™ Z250, Tetric™ Ceram Bleach) cured either by LED or by halogen lamp (HL) were studied using an ...

Data: 2010   |   Origem: Oasisbr

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