Nutritional transition is an important public health issue in developing countries, where switch from undernutrition to overnutrition/obesity is rapidly occurring, often within two or three generations. Such transition is related to changes in lifestyle, with people having more access to western high-caloric diets. In developing countries, settings of poverty, poor sanitation and hygiene are still common, where...
his study aimed to assess the possible systemic antinociceptive activity of mangiferin and to clarify the un- derlying mechanism, using the acute models of chemical (acetic acid, formalin, and capsaicin) and thermal (hot-plate and tail- fl ick) nociception in mice. Mangiferin at oral doses of 10 to 100 mg/kg evidenced signif- icant antinociception against chemogenic pain in the test models of acetic acid-induce...