9 documents found, page 1 of 1
Host‐, Environment‐, or Human‐Related Effects Drive Interspecies Interactions i...
Ferreira, Eduardo M.; Cunha, Mónica V.; Duarte, Elsa L.; Gonçalves, Renata; Pinto, Tiago; Mira, António; Santos, Sara M.In many Mediterranean ecosystems, animal tuberculosis (TB), caused by Mycobacterium bovis, is maintained by multi-host communities in which cattle and different wildlife species establish interaction networks contributing to M. bovis transmission and persistence. Most studies have addressed wildlife–cattle disease-relevant interactions, focusing on reservoir hosts, while disregarding the potential contribution ...
Exposição precoce a micotoxinas: o contributo dos projetos MYCOMIX e earlyMYCO
Alvito, Paula; Bastos-Amador, Patricia; Duarte, Elsa L.; Ferreira, Manuela; Nunes, Carla; Martins, Carla; Assunção, RicardoA exposição a contaminantes químicos nos primeiros 1000 dias de vida tem sido associada a alterações de saúde, constituindo um domínio emergente de pesquisa fundamental para o conhecimento do exposoma humano. As micotoxinas produzidas por fungos integram a lista de contaminantes químicos tóxicos presentes nos alimentos e têm efeitos carcinogénicos, nefrotóxicos, hepatotóxicos e imunossupressores. A mucosa intes...
Mastitis in sheep: a disease to be taken seriously
Queiroga, Maria Cristina; Duarte, Elsa L.; Laranjo, MartaMastitis is the inflammation of the mammary gland, whether infectious or not. Nonetheless, bacteria are the main aetiological agents of this disease. A diversity of bacterial genera and species has been reported to cause mastitis. Mastitis in sheep are the source of serious economic losses due to mortality, premature culling, decreased lamb growth and survival, and reduced milk production. Other negative outcom...
Sheep mastitis Staphylococcus epidermidis biofilm effects on cell adhesion and ...
Queiroga, Maria Cristina; Duarte, Elsa L.; Laranjo, MartaMastitis in sheep is an important disease as it causes a decrease in milk yield and quality. Staphylococcus epi- dermidis is recognized as the main cause of mastitis in sheep. Its ability to produce biofilm is believed to con- tribute to mammary gland pathology. The aim of this study was to assess the influence of S. epidermidis biofilm production on cell adhesion and on the inflammatory response of the mammary...
Evidência para o efeito de um “gene principal” do hospedeiro na suscetibilidade...
David, Susana; Mateus, Ana R.A.; Duarte, Elsa L.; Albuquerque, José; Portugal, Clara; Sancho, Luísa; Lavinha, João; Gonçalves, GuilhermeA análise do genoma do patógeno e da genética do hospedeiro tem possibilitado o entendimento da coevolução do Mycobacterium tuberculosis com o seu hospedeiro humano, conduzindo a relações simpátricas mais estáveis entre o hospedeiro e o patógeno. A influência de fatores clínicos (coinfeção pelo VIH e tuberculose multirresistente (MDRTB]) e demográficos (sexo e idade) na relação hospedeiro-patógeno simpátrica fo...
Determinants of the Sympatric Host-Pathogen Relationship in Tuberculosis
David, Susana; Mateus, A. R. A.; Duarte, Elsa L.; Albuquerque, José; Portugal, Clara; Sancho, Luísa; Lavinha, João; Gonçalves, GuilhermeMajor contributions from pathogen genome analysis and host genetics have equated the possibility of Mycobacterium tuberculosis co-evolution with its human host leading to more stable sympatric host–pathogen relationships. However, the attribution to either sympatric or allopatric categories depends on the resolution or grain of genotypic characterization. We explored the influence on the sympatric host-pathogen...
A real time Taqman RT-PCR for the detection of rabbit hemorrhagic disease virus...
Duarte, Margarida Dias; Carvalho, Carina L.; Barros, Silvia C.; Henriques, Ana M.; Ramos, Fernanda; Fagulha, Teresa; Luís, Tiago; Duarte, Elsa L.As key prey, the wild rabbit downsize constitutes a major drawback on the endangered Iberian lynx (Lynx pardinus) re-introduction in the Iberia. Several captive breeding units mostly located in Alentejo, endeavour the wild rabbit repopulation of depleted areas assigned for the lynx re-introduction. Here we report an RHDV2 outbreak that occurred in early 2016 in a wild rabbit captive breeding unit located in Bar...
Determinants of the Sympatric Host-Pathogen Relationship in Tuberculosis
David, Susana; Mateus, A. R. A.; Duarte, Elsa L.; Albuquerque, José; Portugal, Clara; Sancho, Luísa; Lavinha, João; Gonçalves, GuilhermeMajor contributions from pathogen genome analysis and host genetics have equated the possibility of Mycobacterium tuberculosis co-evolution with its human host leading to more stable sympatric host-pathogen relationships. However, the attribution to either sympatric or allopatric categories depends on the resolution or grain of genotypic characterization. We explored the influence on the sympatric host-pathogen...
Implication of the RDRio Mycobacterium tuberculosis sublineage in multidrug res...
David, Susana; Duarte, Elsa L.; Leite, Clarice Queico Fugimura; Ribeiro, João-Nuno; Maio, José-Nuno; Paixão, Eleonora; Portugal, Clara; Sancho, LuísaMultidrug and extensively drug resistant Mycobacterium tuberculosis are a threat to tuberculosis control programs. Genotyping methods, such as spoligotyping and MIRU–VNTR typing (Mycobacterial Interspersed Repetitive Units), are useful in monitoring potentially epidemic strains and estimating strain phylogenetic lineages and/or genotypic families. M. tuberculosis Latin American Mediterranean (LAM) family is a m...