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XRCC4 rs28360071 intronic variant is associated with increased risk for infant ...

Louzada-Neto,Orlando; Lopes,Bruno A.; Brisson,Gisele D.; Andrade,Francianne G.; Cezar,Ingrid S.; Santos-Rebouças,Cíntia B.; Albano,Rodolpho M.

Abstract Early age acute leukemia (EAL) shows a high frequency of KMT2A-rearrangements (KMT2A-r). Previous investigations highlighted double-strand breaks arising from maternal exposure to xenobiotics during pregnancy as a risk factor for EAL and KMT2A-r. In this case-control study, we investigated the relationship between EAL and genetic variants of the nonhomologous end-joining (XRCC6 rs5751129, XRCC4 rs68693...

Date: 2020   |   Origin: Oasisbr

Effect of pre-anesthetic fasting on gastric emptying and plasma glucose in heal...

Lecheta,Danielle R.; Silva,Dheywid K.M.; Santos,Guilherme A.; Cunha,Marcelo S.; Gaspar,Tamiris T.; Lopes,Bruno A.; Deboleto,Sandriele G.C.

ABSTRACT: Gastric emptying and plasma glucose were evaluated in young and adult dogs, fed with dry and wet food, submitted to different periods of pre-anesthetic fasting (6, 8, and 12 hours). Forty healthy dogs were selected, which were segmented into four groups according to the age group and type of diet. It was evaluated the gastric emptying by ultrasound and serum glycemia. Only 17.5% presented complete gas...

Date: 2020   |   Origin: Oasisbr

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