4 documents found, page 1 of 1
An UPLC-MS/MS Method for Determination of Vicenin-2 and Lychnopholic Acid in Ra...
Gouvea,Dayana R.; Buqui,Gabriela A.; Lopes,João Luis C.; Diniz,Andrea; Lopes,Norberto P.Vicenin-2 (VIC) and lychnopholic acid (LA) are present in large amounts in hydroalcoholic extract from leaves of Lychnophora salicifolia, commonly known in the Brazilian Cerrado as "arnicão", a plant applied as topic anti-inflammatory and as a flavoring agent for the traditional spirit (cachaça). A new ultra-performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS) method was developed and validat...
Spatial and Temporal Variations in Secondary Metabolites Content of the Brazili...
Gobbo-Neto,Leonardo; Bauermeister,Anelize; Sakamoto,Humberto T.; Gouvea,Dayana R.; Lopes,João Luis C.; Lopes,Norberto P.The genus Lychnophora (Asteraceae) is a medicinal plant traditionally used as anti-inflammatory or analgesic agent. Its biological properties have been widely investigated and correlated with its chemical composition, which could be different between the species and even accordingly to the place and season of collection. In this work, it was investigated the spatial and temporal variations in the secondary meta...
In vitro study of antioxidant and scavenger properties of phenolic compounds fr...
Grael,Cristiane F. F.; Kanashiro,Alexandre; Kabeya,Luciana M.; Jordão,Christiane O.; Takeara,Renata; Gobbo-Neto,Leonardo; Polizello,Ana Cristina M.This paper describes the antioxidant effects of thirteen phenolic compounds isolated from plants of the genus Lychnophora. Two assays were performed to evaluate these effects: a cellular test that measured the luminol-enhanced chemiluminescence produced by neutrophils stimulated with opsonized zymosan and a cell-free test involving horseradish peroxidase-H2O2-luminol. In both assays, the antioxidant activity of...
Sesquiterpene lactones from Minasia alpestris
Crotti,Antônio Eduardo M.; Cunha,Wilson R.; Lopes,Norberto P.; Lopes,João Luis C.The chemical investigation of the Minasia alpestris leaves afforded two new furanoheliangolides in addition to seven known sesquiterpene lactones. The structures were elucidated by spectroscopic methods.