Wastewater treatment plants (WWTPs) are essential barriers to attenuate the emission of contaminants, such as antibiotic-resistant bacteria (ARB) and resistance genes (ARGs), which monitoring is becoming a requirement (Directive (EU) 2024/3019). Despite the urgent need to improve wastewater treatment to remove ARB&ARGs, the complexity of microbial community dynamics during treatment remains poorly understood. T...
Antimicrobial resistance genes (ARGs) have rapidly emerged and spread globally, but the pathways driving their spread remain poorly understood. We analyzed 1240 sewage samples from 351 cities across 111 countries, comparing ARGs known to be mobilized with those identified through functional metagenomics (FG). FG ARGs showed stronger associations with bacterial taxa than the acquired ARGs. Network analyses furth...
Understanding global viral dynamics is critical for public health. Traditional surveillance focuses on individual pathogens and symptomatic cases, which may miss asymptomatic infections or newly emerging viruses, delaying detection and response. Wastewater-based epidemiology has been used to track pathogens through targeted molecular assays, but its reliance on predefined targets limits detection of the full vi...
The WHO research agenda for antimicrobial resistance (AMR) in human health has identified 40 research priorities to be addressed by the year 2030. These priorities focus on bacterial and fungal pathogens of crucial importance in addressing AMR, including drug-resistant pathogens causing tuberculosis. These research priorities encompass the entire people-centred journey, covering prevention, diagnosis, and treat...
Aquaponics combines hydroponic crop production with recirculating aquaculture. These systems comprise various compartments ( in this case: fish tank, biofilter, sump, hydroponic floating raft, settler, and aerobic digester provided by Green in Blue ). Efficient developing of aquaponics in terms of water quality, fish welfare, plant health and food safety requires a thorough understanding of the microbial compos...
The occurrence of antimicrobial resistance raises concerns as a human health threat that can be propagated through the environment. Wastewater discharge into the environment is an important source for antibiotic resistant bacteria (ARB) and antibiotic resistance genes (ARGs). Sewage collection and urban wastewater treatment plants (UWTPs) are major barriers that reduce environmental contamination by sewage-deri...