4 documents found, page 1 of 1
Effects of anastrozole on Ki-67 antigen expression in the vaginal epithelium of...
Chagas, Diego Cipriano; Barros-Oliveira, Maria da Conceição; Lopes-Costa, Pedro Vitor; Pereira, Renato de Oliveira; Melo, Mariella de AlmeidaOBJECTIVES: Aromatase inhibitors are the first-choice drugs for the treatment of hormone sensitive breast cancer. However, in addition to the scarcity of studies, there are controversies about their effects on vaginal epithelial cell proliferation in rats, especially those in persistent estrus. METHODS: To investigate vaginal epithelial cell proliferation by Ki-67 antigen expression, persistent estrus was induc...
Genetic polymorphism of calcium-sensing receptor in women with breast cancer
Campos-Verdes, Larysse Maira; Silva-Sampaio, Joao Paulo da; Costa-Silva, Danylo Rafhael; Oliveira, Victor Alves de; Conde Junior, Airton MendesMade available in DSpace on 2018-11-26T15:47:41Z (GMT). No. of bitstreams: 0 Previous issue date: 2018-03-01; Breast cancer is a disease of unknown etiology, whose major risk factors are genetic alterations. Polymorphism of the calcium-sensing receptor (CaSR) has been a focus of some recent studies, due to a probable association with breast cancer risk and tumor aggressiveness. A relationship between polymorphi...
Analysis of the Ki-67 index in the vaginal epithelium of castrated rats treated...
Nery-Aguiar, Afif Rieth; Aguiar, Yousef Qathaf; Conde Júnior, Airton Mendes; Alencar, Airlane Pereira; Tavares, Cleciton Braga; Lopes-Costa, Pedro VitorOBJECTIVES: Vaginal atrophy and breast cancer are common conditions in postmenopausal women and tamoxifen is the standard endocrine treatment for hormone-sensitive tumors. The present study aimed to assess the effect of tamoxifen on Ki-67 protein expression in the vaginal epithelium of castrated rats. MATERIAL AND METHODS: Forty Wistar-Hannover adult, virgin, castrated rats were randomly divided into two groups...
Effects of Raloxifene on Ki-67 and CD34 antigen expression in breast cancer
Lopes-Costa, Pedro Vitor