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Anti‑leishmanial compounds from microbial metabolites: a promising source

Cunha, Ana F. S. da; Di C. Oliveira, Yvanna L.; Dolabella, Silvio S.; Scher, Ricardo; Souto, Eliana B.; Lopez, Jorge A.; Jain, Sona

Leishmania is a complex disease caused by the protozoan parasites and transmitted by female phlebotomine sandfly. The disease affects some of the poorest people on earth with an estimated 700,000 to 1 million new cases annually. The current treatment for leishmaniasis is toxic, long, and limited, in view of the high resistance rate presented by the parasite, necessitating new perspectives for treatment. The dis...


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