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Effect of thermal and chemical treatments used for SARS-COV-2 inactivation in t...

Lamy, Elsa; Rubio, Camila; Carreira, Laura; Capela e Silva, Fernando; Martinez-Subiela, Silvia; Tecles, Fernando; Lopez-Jornet, Pia; Céron, Jose

The present study aims to assess the effects of thermal and chemical inactivating procedures, that can be used for SARS-CoV-2 inactivation, on different salivary analytes. SDS-Polyacrylamide Gel Electrophoresis (SDS-PAGE) protein profile and a panel of 25 specific biomarkers of oxidative status, stress, metabolism and tissue damage were evaluated in samples subjected to different treatments: thermal (65 °C or 9...


Saliva in Health and Disease - The Present and Future of a Unique Sample for Di...

Tvarijonaviciute, Asta; Martinez-Subiela, Silvia; Lopez-Jornet, Pia; Lamy, Elsa

Saliva as a unique sample for health assessment is gaining attention among researchers of different fields in the last 20 years; being reflected in an impressive increase in the number of papers published studying saliva from different biological aspects in human and veterinary species. Once deemed merely a digestive juice is now considered a biological fluid capable of communicating information about physiopat...


Proteomics-based identification of salivary changes in patients with burning mo...

Castillo-Felipe, Candela; Franco-Martínez, Lorena; Tvarijonaviciute, Asta; Lopez-Jornet, Pia; Lamy, Elsa

Burning mouth syndrome (BMS) is a chronic oral condition characterized by an intraoral burning sensation, taste alterations, and dry mouth sensations. Although a number of factors have been closely related to the appearance of the symptoms, including anxiety, depression, and sleep disturbances, the etiology of BMS remains unclear. Furthermore, currently no objective diagnostic tools exist, making its diagnosis ...


Salivary biomarkers in the diagnosis and monitoring of metabolic and endocrine ...

Tvarijonaviciute, Asta; Martinez-Subiela, Silvia; Lopez-Jornet, Pia; Lamy, Elsa

The present chapter revises the current knowledge about the use of salivary biomarkers for metabolic and endocrine disease diagnosis and monitoring in humans and different animal species. Currently, most information available comes from human medicine and studies performed with experimental animals such as mouse or rat, and less from other veterinary species. Furthermore, since obesity and its-related pathologi...


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