3 documents found, page 1 of 1
Choristoma: a very rare cause of thyroid nodule: case report and literature review
Rocha, José Vicente; Cruz, Rafael Moiteiro Da; Alexandre, Maria Inês; Gomes, Ana Raquel; Lopez-Presa, Dolores; Bugalho, Maria JoãoBackground: Choristoma is a well-defined benign lesion formed by histologically normal tissue in an unusual location. Diagnosis is confirmed after surgical removal of the mass. To our knowledge, to date there has been only one case of thyroid choristoma described in the literature. Patient findings: A 70-year-old man with a history of non-Hodgkin lymphoma presented with sudden cervical enlargement. Cervical CT ...
Usefulness of a clinicopathological classification in predicting treatment-rela...
Peixe, Carolina; Alexandre, Maria Inês; Gomes, Ana Raquel; Nobre, Ema; Silva, Ana Luísa; Oliveira, Tiago; Lopez-Presa, Dolores; Faria, ClaudiaPurpose: A clinicopathological classification has been designed to predict recurrence/progression in patients with pituitary adenomas (PAs). We aimed to study its usefulness in predicting PAs that will have a challenging disease course and may require more often complex multimodal and multiple therapeutic approaches. Methods: Retrospective analysis of 129 patients with PAs operated in our institution between 20...
Genomic profiling of sarcomas: a promising weapon in the therapeutic arsenal
Brás, Raquel; Lopez-Presa, Dolores; Esperança Martins, Miguel; Alvim, Cecilia; Gallego Páez, Lina Marcela; Costa, Luis; Fernandes, IsabelSarcomas are rare malignant mesenchymal neoplasms, and the knowledge of tumor biology and genomics is scarce. Chemotherapy is the standard of care in advanced disease, with poor outcomes. Identifying actionable genomic alterations may offer effective salvage therapeutic options when previous lines have failed. Here, we report a retrospective cohort study of sarcoma patients followed at our center and submitted ...