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Effect of exogenous administration of Candida albicans autoregulatory alcohols ...

Martins, Margarida Isabel Barros Coelho; Lazzell, Anna L.; Lopez-Ribot, José L..; Henriques, Mariana; Oliveira, Rosário

Candida albicans supernatants contain a mixture of autoregulatory alcohols. In vitro, when added individually or in combination, these alcohols inhibit the yeast to filamentous form conversion. Here we evaluate the in vivo effect of the exogenous administration of a Cocktail solution simulating the composition of alcohols present in a C. albicans culture supernatant(1 ml; 94 μmol l–1 isoamyl alcohol, 70 μmol l–...


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