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Risk Factors for Breast Cancer, Overall and by Tumor Subtype, among Women from ...

Brandão, M; Guisseve, A; Damasceno, A; Bata, G; Silva-Matos, C; Alberto, M; Ferro, J; Garcia, C; Zaqueu, C; Lorenzoni, C; Leitão, D; Soares, O

Background: Breast cancer incidence is rising in Africa, but there are scare data regarding risk factors in this region. We assessed the relation between risk factors and the occurrence of breast cancer, overall and by tumor subtype in women from Mozambique. Methods: The associations between education, number of births, height, weight, body mass index (BMI), and breast cancer risk among 138 cases (participants ...


Survival Impact and Cost-Effectiveness of a Multidisciplinary Tumor Board for B...

Brandão, M; Guisseve, A; Bata, G; Firmino-Machado, J; Alberto, M; Ferro, J; Garcia, C; Zaqueu, C; Jamisse, A; Lorenzoni, C; Piccart-Gebhart, M

Background Despite the international endorsement of multidisciplinary tumor boards (MTBs) for breast cancer care, implementation is suboptimal worldwide, and evidence regarding their effectiveness in developing countries is lacking. We assessed the impact on survival and the cost-effectiveness of implementing an MTB in Mozambique, sub-Saharan Africa. Materials and Methods This prospective cohort study included ...


Breast cancer subtypes: implications for the treatment and survival of patients...

Brandão, M; Guisseve, A; Bata, G; Alberto, M; Ferro, J; Garcia, C; Zaqueu, C; Lorenzoni, C; Leitão, D; Come, J; Soares, O; Gudo-Morais, A; Schmitt, F

Background. Data regarding breast cancer epidemiology, treatment and survival in Africa are scarce. We aimed to assess the distribution of breast cancer subtypes in Mozambique and its impact on patients’ treatment and survival. The concordance of biomarker assessment between cytological and histological samples was also evaluated. Methods. Prospective cohort study including 210 patients diagnosed between Januar...


Fine needle aspiration cytology in Mozambique: Report of a 15-year experience

Carrilho, C; Ismail, M; Lorenzoni, C; Fernandes, F; Alberto, M; Akrami, K; Funzamo, C; Lunet, N; Schmitt, F

Background Fine needle aspiration cytology (FNAC) is an important diagnostic tool in a range of medical settings. It is fast, quick and a highly accurate diagnostic method and can be used, in settings with minimal laboratory infrastructures. Methods In this report, we describe the experience in the use of FNAC since it is introduction in 1996 in the Anatomical Pathology Service of the Maputo Central Hospital (M...


Cancer incidence in Mozambique in 2015-2016: data from the Maputo Central Hospi...

Carrilho, C; Fontes, F; Tulsidás, S; Lorenzoni, C; Ferro, J; Brandão, M; Ferro, A; Lunet, N

There is scarce information on cancer incidence in Mozambique. We aimed to describe cancer incidence data from the Cancer Registry of the Maputo Central Hospital (MCH) in 2015–2016, for Maputo City dwellers, and to compare the incidence rates with those observed in 1956–1961. Cancers with incidence data in 2015–2016 were identified by the Cancer Registry of the MCH. Crude and age-standardized incident rates (AS...


Spectrum of pediatric cancers in Mozambique: an analysis of hospital and popula...

Carreira, H; Lorenzoni, C; Carrilho, C; Ferro, J; Sultane, T; Garcia, C; Amod, F; Augusto, O; Silva-Matos, C; La Vecchia, C; Lunet, N

The existing data provide little detail about the epidemiology of pediatric cancers in Mozambique. We aimed at characterizing the spectrum of pediatric cancers (0–14 years) diagnosed in Mozambique in two different calendar periods. Data were obtained from the Pathology Department of the Maputo Central Hospital (DP-HCM) (1999–2000 and 2009–2010), which receives virtually all samples for histopathological diagnos...


A contribution for a more accurate estimation of the incidence of Kaposi sarcom...

Carrilho, C; Ferro, J; Lorenzoni, C; Sultane, T; Silva-Matos, C; Lunet, N


Prevalence of Helicobacter pylori infection, chronic gastritis, and intestinal ...

Carrilho, C; Modcoicar, P; Cunha, L; Ismail, M; Guisseve, A; Lorenzoni, C; Fernandes, F; Peleteiro, B; Almeida, R; Figueiredo, C; David, L; Lunet, N

We estimated the prevalence of Helicobacter pylori infection, chronic gastritis, atrophy, and intestinal metaplasia in dyspeptic patients from Maputo Central Hospital, Mozambique and evaluated the relationship between infection and histopathological features of chronic gastritis. Biopsies from 109 consecutive patients observed in 2005-2006 were collected from antrum, incisura angularis, and corpus for histopath...


Chronic atrophic gastritis, intestinal metaplasia, helicobacter pylori virulenc...

Peleteiro, B; Carrilho, C; Modcoicar, P; Cunha, L; Ismail, M; Guisseve, A; Lorenzoni, C; Fernandes, F; Almeida, R; Figueiredo, C|; David, L; Lunet, N


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