2 documents found, page 1 of 1
High-dose nandrolone decanoate induces oxidative stress and inflammation in ret...
Magalhães, Saulo Chaves; Oliveira, Keciany Alves de; Freiras, Paula Alexandre; Gomes, Maria Diana Moreira; Pereira, Leonardo Matta; Boa, Luiz fonteThe non-therapeutic use of the androgenic anabolic steroid Nandrolone Decanoate is popular due to its effects on physical performance and body composition, especially for its lipolytic and anabolic effects associated. However, high doses of such drugs are often associated with a series of pathologies related to unbalanced redox homeostasis, which, in turn, can be linked to inflammation. The oxidative stress ons...
Strenuous Acute Exercise Induces Slow and Fast Twitch-Dependent NADPH Oxidase E...
Alves, Juliana Osório; Pereira, Leonardo Matta; Monteiro, Igor Cabral Coutinho do Rêgo; Santos, Luiz Henrique Pontes dos; Ferraz, Alex Soares MarreirosThe enzymatic complex Nicotinamide Adenine Dinucleotide Phosphate (NADPH) oxidase (NOx) may be the principal source of reactive oxygen species (ROS). The NOX2 and NOX4 isoforms are tissue-dependent and are differentially expressed in slow-twitch fibers (type I fibers) and fast-twitch fibers (type II fibers) of skeletal muscle, making them different markers of ROS metabolism induced by physical exercise. The aim...