54 documents found, page 1 of 6
Ionic liquid-based nanoemulsion as a promising strategy to enhance the bioacces...
Sousa, Vítor; Lüdtke, Fernanda Luisa; Hijo, Ariel A. C. Toledo; Loureiro, Luís; Dias, Oscar; Vicente, A. A.; Pinheiro, A. C.; Geada, PedroDunaliella salina is a unicellular halophile green microalga that presents the capacity to accumulate high amounts of β-carotene, a bioactive compound widely recognized by its health benefits. To fulfil its biological functions, however, β-carotene needs to be bioaccessible, which is challenging as its bioaccessibility is typically low. A promising strategy to overcome β-carotene's low bioaccessibility is its e...
In vitro digestion and cytotoxicity study of cannabidiol-loaded nanostructured ...
Vardanega, Renata; Lüdtke, Fernanda Luisa; Loureiro, Luís; Gonçalves, Raquel F. S.; Martins, Joana T.; Pinheiro, A. C.; Vicente, A. A.Cannabidiol (CBD), a lipophilic compound with promising health benefits, such as analgesic, anti-inflammatory and neuroprotective effects, is characterized by low oral bioavailability, which limit its therapeutic application. To address these limitations, CBD was incorporated into nanostructured lipid carriers (NLCs), either as CBD-rich extract (CBDext) or as an isolate (CBDiso). The resulting systems NLC-CBDex...
The challenging management of acute mesenteric ischemia - too frail or too late?
Pinelo, Andreia; Loureiro, Luís; Mendes, Daniel; Rocha, Henrique; Almeida, Henrique; Queirós, Miguel; Cabral, João; Machado, RuiINTRODUCTION: acute mesenteric ischemia (AMI) presents a life-threatening emergency, requiring a high degree of suspicion for timely diagnosis. Despite advancements in the management of these patients, in-hospital mortality rates remain high. This study aims to assess the outcomes and prognostic factors in patients with AMI. METHODS: A retrospective single-center analysis of all patients undergoing emergent sur...
Physician modified endograft to treat a symptomatic juxta-renal aortic aneurysm...
Guedes da Rocha, Henrique; Loureiro, Luís; Teixeira, Sérgio; Vaz, Carolina; Machado, RuiBACKGROUND: Symptomatic or ruptured juxta-renal aortic aneurysms can be managed through open surgical repair or endovascular approaches, including chimney endovascular aortic repair (chEVAR), off-the-shelf branched devices, or physician-modified endograft (PMEG). PMEG has proven to be a feasible alternative with satisfactory long-term outcomes for such conditions. CASE REPORT: We document the inaugural case of ...
Extra-cranial internal carotid aneurysm repair – the importance of technical de...
Pinelo, Andreia; Mendes, Daniel; Rego, Duarte; Loureiro, Luís; Machado, RuiBACKGROUND: Extracranial internal carotid aneurysms are extremely rare and usually diagnosed as incidental findings although thromboembolic events or rupture can occur. Historically treated by open surgery, endovascular repair is emerging as an alternative. We present our center’s experience with both approaches. CASE REPORTS: Four internal carotid aneurysm cases are presented: Case 1 – 60-year-old male present...
Mid and long-term results of the Supera® stent in femoropopliteal obstructive d...
Pinelo, Andreia; Loureiro, Luís; Veterano, Carlos; Rocha, Henrique; Castro, João; Machado, RuiINTRODUCTION The femoropopliteal biomechanical characteristics make the endovascular treatment of complex lesions particularly challenging. Despite several studies reporting longer patency of femoropopliteal stenting when compared to balloon angioplasty, long-term outcomes are still marginal due to the high rate of restenosis, stent fracture, and thrombosis. This study aims to review the current literature on t...
Acerca dessa coisa a que chamamos literacia em saúde mental
Loureiro, LuísEnquadramento: A literacia em saúde mental é um conceito-chave no panorama da promoção e prevenção em saúde mental, contudo tem sido proposto uma expansão do conceito que pode desvirtuar o seu raio de ação. Objetivo: Analisar criticamente o conceito de literacia em saúde mental e sua evolução, a partir da sua génese e desenvolvimentos ulteriores, perspetivando potencialidades e desafios Principais tópicos em an...
Experiences with remote communication in adult intensive care units during the ...
Cardoso, Ana Filipa; Pires, Miguel Grilo; Cioga, Elisabete; Abalroado, Inês; Santos, Diana; Duque, Filipa Margarida; Loureiro, RicardoObjective: The objective of this review is to explore the lived experiences of critically ill adults, their families, or health care professionals with remote communication in intensive care units (ICUs) during the COVID-19 pandemic. Introduction: Family visiting restrictions in ICUs during the COVID-19 pandemic imposed significant challenges to communication between critically ill adults, their families, and t...
Outflow Rescue of Elbow-Blockade Forearm Arteriovenous Fistulas: Outcomes of Op...
Mendes, Daniel; Almeida, Paulo; Sousa, Clemente Neves; Loureiro, Luís; Teixeira, Sérgio; Rego, Duarte; Norton-de-Matos, AntónioBackground Venous scarring at the elbow is a common problem that can cause early and late forearm arteriovenous fistula (AVF) dysfunction in hemodialysis patients. However, any effort to prolong the long-term patency of distal vascular accesses could benefit the patient's survival, maximizing the use of restricted venous patrimony. This study aims to report a single-center experience in the recovery of distal a...
Light induced amaurosis: a rare symptom of carotid stenosis
Andrade de Almeida, Henrique; Teixeira, Sérgio; Loureiro, Luís; Veiga, Carlos; Mendes, Daniel; Veterano, Carlos; Guedes da Rocha, HenriqueINTRODUCTION: Light induced amaurosis refers to a transient monocular or binocular vision loss triggered by bright lights. Like amaurosis fugax, light induced amaurosis is associated with carotid artery stenosis but they differ from each other in presentation and pathophysiology. It is thought to be an impairment in the regeneration of retinal visual pigments caused by the inability of carotid circulation to su...