3 documents found, page 1 of 1
Molecular investigation of ready-to-eat salads for Giardia duodenalis and Crypt...
Faria, Clarissa Perez; Pereira, Adelaide; Almeida, Daniela; Pinto, Miguel; Lourenço, Ágata; Sousa, Maria do CéuFoodborne outbreaks are often associated with the consumption of salads. However, published studies on the detection of foodborne pathogens in ready-to-eat salads are scarce. The aim of this study was to detect Giardia duodenalis and Cryptosporidium DNA in ready-to-eat salads, by applying techniques of molecular biology to study the frequency of contamination in salads. A total of 100 packages of ready-to-eat s...
Lipidome of extracellular vesicles from Giardia lamblia
Faria, Clarissa Perez; Ferreira, Bárbara; Lourenço, Ágata; Guerra, Inês Calado; Melo, Tânia; Domingues, Pedro; Domingues, Maria do Rosário MarquesExtracellular vesicles (EVs) (exossomes, microvesicles and apoptotic bodies) have been well acknowledged as mediators of intercellular communications in prokaryotes and eukaryotes. Lipids are essential molecular components of EVs but at the moment the knowledge about the lipid composition and the function of lipids in EVs is limited and as for now none lipidomic studies in Giardia EVs was described. Therefore, ...
Giardia lamblia Decreases NF-κB p65RelA Protein Levels and Modulates LPS-Induce...
Faria, Clarissa Perez; Neves, Bruno Miguel; Lourenço, Ágata; Cruz, Maria Teresa; Martins, João D.; Silva, Ana; Pereira, Sónia; Sousa, Maria do CéuThe protozoan Giardia lamblia is the most common cause of parasitic gastrointestinal infection worldwide. The parasite developed sophisticated, yet not completely disclosed, mechanisms to escape immune system and growth in the intestine. To further understand the interaction of G. lamblia with host immune cells, we investigated the ability of parasites to modulate the canonical activation of mouse macrophages (...