57 documents found, page 1 of 6
EUFOREA/EPOS2020 statement on the clinical considerations for CRSwNP care
Hellings, Peter; Alobid, Isam; Anselmo‐Lima, Wilma T.; Bernal‐Sprekelsen, Manuel; Bjermer, Leif; Caulley, Lisa; Chaker, Adam; Constantinidis, JannisFollowing the European Forum for Research and Education in Allergy and Airway Diseases (EUFOREA) treatment algorithm for chronic rhinosinusitis (CRS) with nasal polyps (CRSwNP), patients suffering from severe uncontrolled CRSwNP are recommended to receive oral corticosteroids, (revision) sinus surgery, systemic biologicals and/or aspirin treatment after desensitization (ATAD). Given the major differences in ind...
Digitally‐enabled, patient‐centred care in rhinitis and asthma multimorbidity: ...
Bousquet, Jean; Anto, Josep M.; Sousa-Pinto, Bernardo; Czarlewski, Wienczyslawa; Bedbrook, Anna; Haahtela, Tari; Klimek, Ludger; Pfaar, OliverMASK‐air®, a validated mHealth app (Medical Device regulationClass IIa) has enabled large observational implementation studies in over 58,000 people with allergic rhinitis and/or asthma. It can help to address unmet patient needs in rhinitis and asthma care. MASK‐air® is a Good Practice of DG Santé on digitally‐enabled, patient‐centred care. Itis also a candidate Good Practice ofOECD (Organisation for EconomicC...
Clinical and Pharmacotherapeutic Profile of Patients with Type 2 Diabetes Melli...
Lopes, António Cabral; Lourenço, Olga; Roque, Maria de Fátima dos Santos Marques; Morgado, Manuel Augusto Nunes Vicente PassosType 2 diabetes mellitus (T2DM) is closely associated with other pathologies, which may require complex therapeutic approaches. We aim to characterize the clinical and pharmacological profile of T2DM patients admitted to an emergency department. Patients aged ≥65 years and who were already using at least one antidiabetic drug were included in this analysis. Blood glycemia, creatinine, aspartate aminotransferase...
Gastrointestinal disorders potentially associated with Semaglutide: an analysis...
Lopes, António Cabral; Roque, Maria de Fátima dos Santos Marques; Lourenço, Olga; Herdeiro, Maria Teresa; Morgado, Manuel Augusto Nunes Vicente PassosBackground: Semaglutide is a Glucagon-like peptide-1 receptor agonist used in the second-line treatment of poorly controlled type 2 diabetes and can be used in monotherapy or associated with other oral antidiabetics or even insulin, increasing the effectiveness of the treatment. This work aims to analyze the profile of adverse drug reactions reported for semaglutide in Eudravigilance. Research design and method...
Rhinitis associated with asthma is distinct from rhinitis alone: TARIA‐MeDALL h...
Bousquet, Jean; Melén, Erik; Haahtela, Tari; Koppelman, Gerard; Togias, Alkis; Valenta, Rudolf; Akdis, Cezmi; Czarlewski, Wienczyslawa; Rothenberg, MarcAsthma, rhinitis, and atopic dermatitis (AD) are interrelated clinical phenotypes that partly overlap in the human interactome. The concept of “one-airway-one-disease,” coined over 20 years ago, is a simplistic approach of the links between upper- and lower-airway allergic diseases. With new data, it is time to reassess the concept. This article reviews (i) the clinical observations that led to Allergic Rhiniti...
Avoidance Measures for Patients with Allergic Rhinitis: A Scoping Review
Tomé, Miguel Alexandre da Silva; Lourenço, OlgaEnvironmental allergen control is recommended as an essential part of allergic rhinitis (AR) management guidelines. In this scoping review, our objective is to identify measures of allergen avoidance and to evaluate their effectiveness in the management of AR. We conducted systematic searches for randomized controlled trials and observational studies in PubMed, the Cochrane Central Register of Controlled Trials...
Patient‐centered digital biomarkers for allergic respiratory diseases and asthm...
Bousquet, Jean; Shamji, Mohamed; Anto, Josep M.; Schünemann, Holger; Canonica, Giorgio Walter; Jutel, Marek; Del Giacco, Stafano; Zuberbier, TorstenBiomarkers for the diagnosis, treatment and follow-up of patients with rhinitis and/ or asthma are urgently needed. Although some biologic biomarkers exist in specialist care for asthma, they cannot be largely used in primary care. There are no validated biomarkers in rhinitis or allergen immunotherapy (AIT) that can be used in clinical practice. The digital transformation of health and health care (including m...
The impact of implementing an allergic rhinitis clinical management pathway (AR...
House, Rachel; Kritikos, Vicky; Cvetkovski, Biljana; Rimmer, Janet; Yan, Kwok; Cheong, Lynn; Bousquet, Jean; Lourenço, Olga; Bosnic-Anticevich, SinthiaBackground The Allergic Rhinitis Clinical Management Pathway (AR-CMaP) was developed to overcome the challenge of implementing current AR guidelines in the Australian community pharmacy practice and support pharmacists in optimally managing patients' AR. Objective(s) To evaluate the impact of AR-CMaP on patients' behaviour and pharmacists' needs in managing AR in the pharmacy. Methods This study used a cross-se...
HLA‐A23/HLA‐A24 serotypes and dementia interaction in the elderly: Association ...
Cardoso, Elsa M.; Gomes, Vânia Lourenço; Esgalhado, André J.; Ferreira, Débora Reste; Oliveira, Nádia; Amaral, Ana Saraiva; Martinho, AntónioMHC class I molecules regulate brain development and plasticity in mice and HLA class I molecules are associated with brain disorders in humans. We investigated the relationship between plasma-derived soluble human HLA class I molecules (sHLA class I), HLA class I serotypes and dementia. A cohort of HLA class I serotyped elderly subjects with no dementia/predementia (NpD, n = 28), or with dementia (D, n = 28) w...
Management of allergic rhinitis symptoms in the pharmacy Pocket guide 2022
Lourenço, Olga; Cvetkovski, Biljana; Kritikos, Vicky; House, Rachel; Scheire, Sophie; Costa, Elísio; Fonseca, Joao A; Menditto, Enrica; Bedbrook, AnnaThis research received no specific grant from any funding agency in the public, commercial, or not‐for‐profit sectors. Open access funding enabled and organized by Projekt DEAL; Background: Allergic rhinitis (AR) management requires a coordinated effort from healthcare providers and patients. Pharmacists are key members of these integrated care pathways resolving medication-related problems, optimizing regimens...