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ARIA-Italy managing allergic rhinitis and asthma in a changing world: The role ...

Paoletti, Giovanni; Giua, Corrado; Marti, Alessandro; Baio, Matteo Alberto; Valli, Nicolò; Ridolo, Erminia; Ventura, Maria Teresa; Passalacqua, Giovanni

Allergic rhinitis (AR) and asthma are common respiratory disorders that often occur together, affecting quality of life and increasing healthcare expenses of patients. These chronic illnesses are often managed without medical supervision, creating distinct challenges. A lack of resources can limit regular follow-up, which in turn promotes disease mismanagement and an increased reliance on self-medication, inclu...

Date: 2025   |   Origin: uBibliorum

Acute Kidney Injury and Electrolyte Imbalances Caused by Dapagliflozin Short-Te...

Lopes, António Cabral; Lourenço, Olga; Morgado, Sandra; Gaspar, Andreia; Freire, Idalina; Eusébio, Inês; Ribeiro, João; Silva, Mafalda; Mendes, Marta

Dapagliflozin, a sodium–glucose cotransporter 2 inhibitor (SGLT2i), has shown demonstrated benefits for renal and cardiovascular outcomes in large clinical trials. However, short-term concerns regarding its impact on renal function and electrolyte balance exist. This study aimed to evaluate the short-term effects of dapagliflozin on renal function and electrolyte balance in patients newly prescribed the medicat...

Date: 2024   |   Origin: uBibliorum

SGLT2i and GLP1RA effects in patients followed in a hospital diabetology consul...

Lopes, António Cabral; Lourenço, Olga; Morgado, Manuel Augusto Nunes Vicente Passos

Abstract Background: We aimed to investigate the effects of sodium-glucose cotransporter 2 inhibitors (SGLT2i) and glucagon-like peptide-1 receptor agonists (GLP1RA) in patients with type 2 diabetes mellitus (T2DM) in clinical practice. Research design and methods: A total of 340 patients were included. Data on age, gender, antidiabetic medications, and bioanalytical parameters were collected at baseline and on...

Date: 2024   |   Origin: uBibliorum

The future of allergic rhinitis management: A partnership between healthcare pr...

Cvetkovski, Biljana; Muscat, Danielle; Bousquet, Jean; Cabrera, Martha; House, Rachel; Katsoulotos, Gregory; Lourenço, Olga; Papadopoulos, Nikolaos

Allergic rhinitis (AR) is a chronic respiratory condition that internationally continues to be burdensome and impacts quality of life. Despite availability of medicines and guidelines for healthcare providers for the optimal management of AR, optimisation of its management in the community continues to be elusive. The reasons for this are multi-faceted and include both environmental and healthcare related facto...

Date: 2024   |   Origin: uBibliorum

EUFOREA/EPOS2020 statement on the clinical considerations for CRSwNP care

Hellings, Peter; Alobid, Isam; Anselmo‐Lima, Wilma T.; Bernal‐Sprekelsen, Manuel; Bjermer, Leif; Caulley, Lisa; Chaker, Adam; Constantinidis, Jannis

Following the European Forum for Research and Education in Allergy and Airway Diseases (EUFOREA) treatment algorithm for chronic rhinosinusitis (CRS) with nasal polyps (CRSwNP), patients suffering from severe uncontrolled CRSwNP are recommended to receive oral corticosteroids, (revision) sinus surgery, systemic biologicals and/or aspirin treatment after desensitization (ATAD). Given the major differences in ind...

Date: 2024   |   Origin: uBibliorum

Use of and Beliefs toward Novel Tobacco and Nicotine Products among Portuguese ...

Vaz, Marina; Cascais, Pedro; Lourenço, Olga

Over the last decade, novel tobacco and nicotine product experimentation and use have dramatically increased among the youth, even in countries with strong tobacco control and antismoking social norms. We performed an online questionnaire-based cross-sectional study in MarchJune 2021, targeting students from the University of Beira Interior, Portugal. The aim was to assess the experimentation and use of tobacco...

Date: 2024   |   Origin: uBibliorum

Concepts for the Development of Person-Centered, Digitally Enabled, Artificial ...

Bousquet, Jean; Schünemann, Holger; Sousa-Pinto, Bernardo; Zuberbier, Torsten; Togias, Alkis; Samoliński, Bolesław; Bedbrook, Anna

Abstract The traditional healthcare model is focused on diseases (medicine and natural science) and does not acknowledge patients' resources and abilities to be experts in their own lives based on their lived experiences. Improving healthcare safety, quality, and coordination, as well as quality of life, is an important aim in the care of patients with chronic conditions. Person-centered care needs to ensure th...

Date: 2024   |   Origin: uBibliorum

Digitally-enabled, patient-centred care in rhinitis and asthma multimorbidity: ...

Bousquet, Jean; Anto, Josep M; Sousa-Pinto, Bernardo; Czarlewski, Wienczyslawa; Bedbrook, Anna; Haahtela, Tari; Klimek, Ludger; Pfaar, Oliver

MASK-air® , a validated mHealth app (Medical Device regulation Class IIa) has enabled large observational implementation studies in over 58,000 people with allergic rhinitis and/or asthma. It can help to address unmet patient needs in rhinitis and asthma care. MASK-air® is a Good Practice of DG Santé on digitally-enabled, patient-centred care. It is also a candidate Good Practice of OECD (Organisation for Econo...


Rhinitis associated with asthma is distinct from rhinitis alone: TARIA‐MeDALL h...

Bousquet, Jean; Melén, Erik; Haahtela, Tari; Koppelman, Gerard; Togias, Alkis; Valenta, Rudolf; Akdis, Cezmi; Czarlewski, Wienczyslawa; Rothenberg, Marc

Asthma, rhinitis, and atopic dermatitis (AD) are interrelated clinical phenotypes that partly overlap in the human interactome. The concept of “one-airway-one-disease,” coined over 20 years ago, is a simplistic approach of the links between upper- and lower-airway allergic diseases. With new data, it is time to reassess the concept. This article reviews (i) the clinical observations that led to Allergic Rhiniti...

Date: 2023   |   Origin: uBibliorum

Gastrointestinal disorders potentially associated with Semaglutide: an analysis...

Lopes, António Cabral; Roque, Maria de Fátima dos Santos Marques; Lourenço, Olga; Herdeiro, Maria Teresa; Morgado, Manuel Augusto Nunes Vicente Passos

Background: Semaglutide is a Glucagon-like peptide-1 receptor agonist used in the second-line treatment of poorly controlled type 2 diabetes and can be used in monotherapy or associated with other oral antidiabetics or even insulin, increasing the effectiveness of the treatment. This work aims to analyze the profile of adverse drug reactions reported for semaglutide in Eudravigilance. Research design and method...

Date: 2023   |   Origin: uBibliorum

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