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Adherence to mediterranean diet and aromatic plants intake are related with gus...

Louro, T; Castelo, PM; Simões, C; Capela e Silva, F; Luís, H; Moreira, Pedro; Lamy, E


The Influence of (Poly)phenol Intake in Saliva Proteome: Short- and Medium-Term...

Louro, T; Carreira, L; Caeiro, I; Simões, C; Ricardo Rodrigues, S; Rato, AE; Capela e Silva, F; Luís, H; Moreira, Pedro; Lamy, E

<jats:p>The relationship between salivary proteome and dietary habits was studied in previous works, where a relationship between salivary proteins like cystatins and polyphenol/tannin levels in diet was observed. However, it remains to be elucidated if this association results from an effect of polyphenol-rich food ingestion on saliva composition. The aim of this work was to test the effects of apple intake on...


How Individual Variations in the Perception of Basic Tastes and Astringency Rel...

Louro, T; Simoes, C; Castelo, PM; Silva, FCE; Luis, H; Moreira, Pedro; Lamy, E

Background: Oral food perception plays a major role in food acceptance, although the way it relates with food preferences and final choices in adults is still debatable. The objective of the present study was to assess the relationship between gustatory function, dietary habits and fruit and vegetable preferences. Methods: Recognition thresholds, suprathreshold and hedonics were accessed for sweet, bitter, sour...


Salivary Protein Profile and Food Intake: A Dietary Pattern Analysis

Louro, T; Simões, C; Lima, W; Carreira, L; Castelo, PM; Luis, H; Moreira, Pedro; Lamy, E

Saliva research has gained interest due to its potential as a source of biomarkers. One of the factors inducing changes in saliva, in the short term, is food intake, and evidence exist about changes in salivary proteome induced by some food components. Since this topic of research is in its early stages, it was hypothesized that saliva protein composition could be associated with different levels of adherence t...


Relationship between Mediterranean Diet Adherence and Saliva Composition

Louro, T; Simoes, C; Penetra, MJ; Carreira, L; Castelo, PM; Luis, H; Moreira, Pedro; Lamy, E

Dietary polyphenol exposure is known to change protein saliva composition in rodents, but less is known in humans. The present study aimed to assess the relationship between saliva protein composition and adherence to Mediterranean Diet (MD) and polyphenol intake levels. Participants were assessed for their dietary habits, which were converted in Mediterranean adherence level, according to Mediterranean Diet Ad...


Antioxidant and vascular effects of gliclazide in type 2 diabetic rats fed high...

Sena, CM; Louro, T; Matafome, P; Nunes, E; Monteiro, P; Seiça, R

Diabetes mellitus is characterized by oxidative stress, which in turn determines endothelial dysfunction. Gliclazide is a sulphonylurea antidiabetic drug with antioxidant effects due to its azabicyclo-octyl ring. It has been reported to potentially protect the vasculature through improvements in plasma lipid levels and platelet function. We hypothesized that gliclazide has a beneficial effect on endothelial fun...


A role for atorvastatin and insulin combination in protecting from liver injury...

Matafome, P; Nunes, E; Louro, T; Amaral, C; Crisóstomo, J; Rodrigues, L; Moedas, AR; Monteiro, P; Cipriano, MA; Seiça, R

Non-alcoholic fatty liver disease (NAFLD) is a major complication linked with the metabolic syndrome associated with dyslipidemia, inflammation, and oxidative stress. Impact of type 2 diabetes with hyperlipidemia in NAFLD has to be established, as well as the utility of commonly prescribed anti-diabetic and lipid-lowering agents in improving liver injury markers. Genetic type 2 diabetic Goto-Kakizaki rats were ...


Disfunção Endotelial na Diabetes Tipo 2: Efeito de Antioxidantes

Sena, CM; Nunes, E; Louro, T; Proença, T; Seiça, RM

Individuals with insulin resistance and diabetes mellitus have increased cardiovascular morbidity and mortality, caused in part by vascular complications. Endothelial dysfunction has been implicated in the pathogenesis of vascular diabetic disease. This abnormal function of the vasculature precedes cardiovascular disease and is associated with impaired endothelium-dependent vasorelaxation. The main etiology of ...


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