Endometrial adenocarcinoma is one of the most frequent malignant neoplasms of the female genital tract in Western Europe and North America. More than 90% of cases occur in women over 50 years-old, however, 4% of cases occur before 40 years-old. The present clinical case concerns a 74 years-old woman with blood loss, a vaginal ulcerated lesion, and an enlarged uterus. She consequently underwent a colpocytology, ...
Background: Pleural effusion (PE) is common in advanced-stage lung cancer patients and is related to poor prognosis. Identification of cancer cells is the standard method for the diagnosis of a malignant PE (MPE). However, it only has moderate sensitivity. Thus, more sensitive diagnostic tools are urgently needed. Methods: The present study aimed to discover potential protein targets to distinguish malignant pl...
Access to genetic testing and counselling in remote areas such as the Madeira archipelago, in the Northern Atlantic Ocean, may be complex. Different counselling methods, including telegenetics, should be explored. In this study, we characterise the Hereditary Breast/Ovarian Cancer (HBOC) families with Madeira ancestry enrolled in our programme. Of a total of 3, 566 index patients tested between January 2000 and...
Wernicke-Korsakoff syndrome (WKS) is a life-threatening and underdiagnosed neuropsychiatric condition caused by thiamine deficiency that comprises Wernicke encephalopathy and Korsakoff syndrome. Although mainly associated with chronic alcoholism, WKS can arise from other circumstances. This report describes a series of cases of WKS that were clinically evaluated by liaison psychiatrists on a nonpsychiatric inpa...
O presente estudo reporta a citologia de uma mulher de 66 anos, que apresenta um epitélio atrófico com fundo inflamatório. Identificaram-se agregados tridimensionais de células glandulares com sobreposição celular, anisocariose, aumento nuclear, hipercromasia moderada, presença de nucléolos e cromatina grosseira, irregularmente distribuída. O diagnóstico citológico foi de células glandulares atípicas sem outra ...
With the objective of determining the pattern and decision making process in using antipsychotic drugs in patients admitted to hospital for acute psychotic disorder we have made a retrospective analysis in 244 in-patients in 7 hospitals for mental disorders. We have selected two groups, IM and PO, that in the first three days of internment have received either intravenous antipsychotic medication or oral medica...
As far as we know, there is no experience of quality management in mental health care in Portugal. This study fills a gap in the area of consultation-liaison psychiatry. Due to its multidisciplinarity and to the complexity of the problems it deals with, consultation-liaison psychiatry seems a privileged field for the development of this kind of programme. The authors describe the different steps necessary for t...