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MMPs at Work

Patrão, Mariana Ramos; Pereira, Pedro Mariano; Caldeira, Jorge; Salema-Oom, Madalena

Matrix metallopeptidases (MMPs) are enzymes that, in balance with their inhibitors, play a vital role in extracellular matrix remodelling, particularly during orthodontic tooth movement (OTM). Despite growing interest, significant research is still required to fully comprehend the mechanisms and signalling pathways involved in periodontal ligament remodelling and OTM, particularly those mediated by MMPs. This r...


Criteria for early diagnosis of third molar agenesis : a retrospective radiogra...

Dumas, Margaux; Pereira, Pedro Mariano; Bugaighis, Iman; Retto, Paulo Fernandes; Proença, Luís

Objective: To explore the association between chronological, dental and skeletal ages and early diagnosis of third molars agenesis. Material and methods: This retrospective radiographic study comprised a sample of 282 Portuguese patients (122 males and 160 females) who sought orthodontic treatment between 2007 and 2018. Each participant had panoramic and lateral cephalometric radiographs performed before and af...


Comparison of shear bond strength of metallic brackets bonded to ceramic surfac...

Pulido, María Belén Paz; Pereira, Pedro Mariano; Pitschielller, Ricardo; Proença, Luís; Bugaighis, Iman

OBJECTIVE: To compare the shear bond strength (SBS) of orthodontic brackets bonded to three different types of ceramic surfaces (feldspathic, lithium disilicate, and zirconium) using Assure® Plus All and Transbond™ XT adhesives. MATERIALS AND METHODS: The sample comprised 72 monolithic computer-aided design and computer-aided manufacturing (CAD/CAM) ceramic samples that were randomly divided into six groups of ...


The effect of ceramic surface conditioning on bond strength of metallic bracket...

Ferreira, Rita; Pereira, Pedro Mariano; Pitschieller, Ricardo; Proença, Luís; Bugaighis, Iman

Objective: To compare the shear bond strength (SBS) of brackets bonded to three different types of ceramic surfaces (feldspathic ceramic, lithium disilicate ceramic, and zirconia), conditioned with either hydrofluoric acid or sandblasting, using Assure® Plus All bonding agent. Materials and methods: A total of 72 monolithic CAD/CAM ceramic specimens were divided into six groups of 12 samples. Three groups (G1: ...


The effect of different reconditioning methods on bond strength of rebonded bra...

Pereira, Pedro Mariano; Bugaighis, Iman; Matos, Pedro M.; Proença, Luís

AIM: To evaluate the effect of three different reconditioning techniques on the shear bond strength (SBS) of rebonded brackets. MATERIALS AND METHODS: Forty-five orthodontic brackets were bonded to human premolar teeth using Transbond™ XT. After debonding, the samples were randomly assigned into equal groups to assess three techniques for the removal of residual adhesive from bracket bases: in Group A, each bra...


Miniscrew-assisted rapid palatal expansion (MARPE) : an umbrella review

Ventura, Vanda; Botelho, João; Machado, Vanessa; Mascarenhas, Paulo; Pereira, François Durand; Mendes, José João; Delgado, Ana Sintra

In postpubertal patients, maxillary transverse discrepancy is a common condition often requiring surgical approaches. To overcome the excess morbidity and discomfort, maxillary expansion through miniscrew-assisted rapid palatal expansion (MARPE) was proposed and studied in the last few years. This umbrella review aims to critically appraise the quality of evidence and the main clinical outcomes of available sys...


Perception of need for further refinement in a clear aligner treatment among or...

Oliveira, Patrícia; Bugaighis, Iman; Costa, Hélder Nunes; Pereira, Pedro Mariano

Clear aligner treatment often requires further refinement to improve the orthodontic treatment outcome. However, the perceptions of treatment outcomes evaluated by orthodontists and dentists are sparse, and laypeople’s perceptions have yet to be explored. Here, we explore the perceptions of orthodontists, dentists, and laypeople concerning the treatment outcomes achieved after completing the first sequence of a...




Avaliação da perceção estética do perfil facial em diferentes painéis de observ...

Viegas, Marta M.; Pereira, Pedro Mariano; Proença, Luís

Objetivo: Avaliar se a perceção estética da convexidade do perfil facial é semelhante entre os diferentes painéis de avaliadores. Métodos: Foram utilizadas silhuetas de perfil construídas no programa Adobe Photoshop Cs5®. A partir de um perfil de referência com 12° de convexidade facial foram criadas 4 silhuetas com convexidade de 0°, 6°, 18° e 24°. Foram avaliadas por especialistas em ortodontia, estudantes de...


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