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Acrocomia aculeata associated with doxorubicin: cardioprotection and anticancer...

Monteiro-Alfredo, Tamaeh; Dos Santos, Jéssica Maurino; Antunes, Kátia Ávila; Cunha, Janielle; da Silva Baldivia, Debora; Pires, Ana Salomé

Doxorubicin (Dox) is a chemotherapeutic agent widely used in the clinic, whose side effects include cardiotoxicity, associated with decreased antioxidant defenses and increased oxidative stress. The association of Dox with natural antioxidants can extend its use if not interfering with its pharmacological potential. In this study, we aimed to understand the effects and mechanisms of the aqueous extract of Acroc...

Date: 2023   |   Origin: Estudo Geral - Universidade de Coimbra
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