3 documents found, page 1 of 1
Curcumin reversion of neurochemical and immunohistochemical alterations in brai...
Lucetti, Elaine Cristina Pereira; Lucetti, Daniel Luna; Ribeiro, Ana Elisa da Silva; Moura, Rafael Barbosa de; Sampaio, Thayga Maria AraújoStroke is one leading cause of mortality and morbidity worldwide where free radicals production and inflammation play important roles. Curcumin, a curcuminoid from Curcuma longa presents several biological properties and is a potent anti-inflammatory and antioxidant agent. The objectives were to study the neuroprotective effects of curcumin on ischemic pups from mothers treated with this drug (25, 50 or 100 mg/...
Efeitos neuroprotetores da curcumina durante o desenvolvimento de ratos submeti...
Lucetti, Elaine Cristina PereiraThe ischemic stroke precipitates a cascade of events that involve excitotoxicity, inflammation, oxidative stress and cell death. Curcumin has demonstrated neuroprotective effects, with antioxidant and antiinflammatory properties. Therefore, we aimed to study these effects of curcumin on experimental model of global cerebral ischemia in rats under development. Methods: Wistar female rats treatment began 24 hours...
Efeitos centrais da cumarina (1,2-Benzopirona) : estudo comportamental e neuroq...
Lucetti, Elaine Cristina PereiraCoumarin (1,2-benzopyrone) is an aromatic compound found in many plant species. This study proposed to evaluate the coumarin actions in behavioral models of anxiety, depression and sedation activity, such as the open field, rota rod, elevated plus maze (EPM), hole board and tail suspension, still looking to clarify mechanisms by which this compound acts, through amino acids determination studies in mice prefron...