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Untargeted metabolomics and in vitro functional analysis unravel the intraspeci...

Pereira, Antia Gonzalez; Cassani, Lucia; Oludemi, Taofiq; Chamorro, Franklin; Calhelha, Ricardo C.; Prieto Lage, Miguel A.; Barros, Lillian

The Camellia genus comprises a vast array of underexplored medicinal plants that merit a systematic valorization to exploit their potential as natural sources of phytochemicals with associated health-promoting properties. In this work, flower extracts from eight poorly characterized Camellia japonica L. cultivars were subjected to polyphenol profiling through untargeted metabolomics combined with in vitro funct...

Date: 2023   |   Origin: Biblioteca Digital do IPB

Algal nutraceuticals: a perspective on metabolic diversity, current food applic...

Garcia-Perez, Pascual; Cassani, Lucia; Garcia-Oliveira, Paula; Xiao, Jianbo; Simal-Gandara, Jesus; Prieto Lage, Miguel A.; Lucini, Luigi

The current consumers’ demand for food naturalness is urging the search for new functional foods of natural origin with enhanced health-promoting properties. In this sense, algae constitute an underexplored biological source of nutraceuticals that can be used to fortify food products. Both marine macroalgae (or seaweeds) and microalgae exhibit a myriad of chemical constituents with associated features as a resu...

Date: 2023   |   Origin: Biblioteca Digital do IPB

Bioaccessibility and bioactive potential of different phytochemical classes fro...

Nicolescu, Alexandru; Babotă, Mihai; Barros, Lillian; Lucini, Luigi; Tanase, Corneliu; Mocan, Andrei; Bunea, Claudiu I.; Crisan, Gianina

Nutraceuticals and functional foods are composed of especially complex matrices, with polyphenols, carotenoids, minerals, and vitamins, among others, being the main classes of phytochemicals involved in their bioactivities. Despite their wide use, further investigations are needed to certify the proper release of these phytochemicals into the gastrointestinal medium, where the bioaccessibility assay is one of t...

Date: 2023   |   Origin: Biblioteca Digital do IPB

Untargeted phytochemical profiling and biological activity of small yellow onio...

Moldovan, Cadmiel; Frumuzachi, Oleg; Babotă, Mihai; Pinela, José; Barros, Lillian; Rocchetti, Gabriele; López, Víctor; Lucini, Luigi; Crisan, Gianina

This study examined the phytochemical profiles (mainly phenolics, carotenoids, and organosulfur compounds) and biological effects of hydroalcoholic extracts of Allium flavum (AF), a species of the Allium genus commonly known as small yellow onion. Unsupervised and supervised statistical approaches revealed clear differences between extracts prepared with samples collected from different areas of Romania. Overal...

Date: 2023   |   Origin: Biblioteca Digital do IPB

Optimized ultrasound-assisted extraction of phenolic compounds from Thymus como...

Babotă, Mihai; Frumuzachi, Oleg; Gâvan, Alexandru; Iacoviță, Cristian; Pinela, José; Barros, Lillian; Ferreira, Isabel C.F.R.; Zhang, Leilei

An optimized ultrasound-assisted extractive method was developed to obtain a polyphenol-enriched extract from the aerial parts of Thymus comosus Heuff. ex Griseb. et Schenk. Optimization process was conducted based on Design of Experiment (DoE) principles, determining the influence of three independent variables (time, ultrasound amplitude, ethanol concentration) on the total phenolic content of the extract (de...

Date: 2022   |   Origin: Biblioteca Digital do IPB

Plant cell cultures of Nordic berry species: Phenolic and carotenoid profiling ...

Rischer, Heiko; Nohynek, Liisa; Puupponen-Pimiä, Riitta; Aguiar, Joselin; Rocchetti, Gabriele; Lucini, Luigi; Câmara, José S.; Mendanha Cruz, Thiago

Plant cell cultures from cloudberry (CL), lingonberry (LI), stone berry (ST), arctic bramble (AB), and strawberry (SB) were studied in terms of their polyphenol and carotenoid composition, antioxidant activity, antihemolytic activity and cytotoxicity effects on cancerous cells. High-resolution mass spectrometry data showed that LI, presented the highest antioxidant activity, contained the highest contents of fl...


Bee Products: A Representation of Biodiversity, Sustainability, and Health

Durazzo, Alessandra; Lucarini, Massimo; Plutino, Manuela; Lucini, Luigi; Aromolo, Rita; Martinelli, Erika; Souto, Eliana B.; Santini, Antonello

Biodiversity strengthens the productivity of any ecosystem (agricultural land, forest, lake, etc.). The loss of biodiversity contributes to food and energy insecurity; increases vulnerability to natural disasters, such as floods or tropical storms; and decreases the quality of both life and health. Wild and managed bees play a key role in maintaining the biodiversity and in the recovery and restoration of degra...


Antioxidant properties of bee products derived from medicinal plants as beekeep...

Durazzo, Alessandra; Lucarini, Massimo; Plutino, Manuela; Pignatti, Giuseppe; Karabagias, Ioannis K.; Martinelli, Erika; Souto, Eliana B.

Plant species are fundamental source of nectar in beekeeping since bees access nectar and pollen from flowers. Consequently, bee products are strongly linked to the bee foraging flora source, and, depending on this, they acquire defined features, including their health and medicinal properties. Medicinal plants contribute greatly to increase the beneficial properties of bee products, such as honey, pollen, roya...


Bee products: a representation of biodiversity, sustainability, and health

Durazzo, Alessandra; Lucarini, Massimo; Plutino, Manuela; Lucini, Luigi; Aromolo, Rita; Martinelli, Erika; Souto, Eliana B.; Santini, Antonello

Biodiversity strengthens the productivity of any ecosystem (agricultural land, forest, lake, etc.). The loss of biodiversity contributes to food and energy insecurity; increases vulnerability to natural disasters, such as floods or tropical storms; and decreases the quality of both life and health. Wild and managed bees play a key role in maintaining the biodiversity and in the recovery and restoration of degra...


Leaf proteome modulation and cytological features of seagrass Cymodocea nodosa ...

Piro, Amalia; Bernardo, Letizia; Serra, Ilia Anna; Barrote, Isabel; Olivé, Irene; Costa, Monya M.; Lucini, Luigi; Santos, Rui; Mazzuca, Silvia

Seagrass Cymodocea nodosa was sampled off the Vulcano island, in the vicinity of a submarine volcanic vent. Leaf samples were collected from plants growing in a naturally acidified site, influenced by the long-term exposure to high CO2 emissions, and compared with others collected in a nearby meadow living at normal pCO2 conditions. The differential accumulated proteins in leaves growing in the two contrasting ...


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