Objectives: This study has used a combination of clinical information, spoligotyping, and georeferencing system to elucidate the genetic diversity of the Mycobacterium tuberculosis isolates circulating in a TB-prevalent municipality of Northeast Brazil. Methods: A total of 115 M. tuberculosis strains were isolated from pulmonary tuberculosis patients from January 2007 to March 2008 in Fortaleza. Drug susceptibi...
The tuberculosis (TB) disease is caused by the bacillus Mycobacterium tuberculosis, which is transmitted by aerosols of patients with active tuberculosis. About two billion people are infected worldwide, with 3.6% of multidrug resistant TB, which means resistant to rifampicin and isoniazid. To control this disease, is necessary the early diagnosis, treatment, and chemoprophylaxis of susceptible individuals, and...