2 documents found, page 1 of 1
Interaction Between NOS3 and HMOX1 on Antihypertensive Drug Responsiveness in P...
Sandrim,Valeria Cristina; Luizon,Marcelo Rizzatti; Pilan,Eliane; Caldeira-Dias,Mayara; Coeli-Lacchini,Fernanda Borchers; Kors,Georgia; Berndt,IulyAbstract Objective We examined the interaction of polymorphisms in the genes heme oxygenase- 1 (HMOX1) and nitric oxide synthase (NOS3) in patients with preeclampsia (PE) as well as the responsiveness to methyldopa and to total antihypertensive therapy. Methods The genes HMOX1 (rs2071746, A/T) and NOS3 (rs1799983, G/T) were genotyped using TaqMan allele discrimination assays (Applied Biosystems, Foster City, CA...
Y-STR diversity and ethnic admixture in White and Mulatto Brazilian population ...
Ferreira,Luzitano Brandão; Mendes-Junior,Celso Teixeira; Wiezel,Cláudia Emília Vieira; Luizon,Marcelo Rizzatti; Simões,Aguinaldo LuizWe investigated 50 Mulatto and 120 White Brazilians for the Y-chromosome short tandem repeat (Y-STR) markers (DYS19, DYS390, DYS391, DYS392 and DYS393) and found 79 different haplotypes in the White and 35 in the Mulatto sample. Admixture estimates based on allele frequencies showed that the admixture of the white sample was 89% European, 6% African and 5% Amerindian while the Mulatto sample was 93% European an...