4 documents found, page 1 of 1
Estudo da via PI3K/AKT/PTEN no câncer: revisão sistemática com metanálise da me...
Luna, Ealber Carvalho MacedoOral squamous cell carcinoma (OSCC) represents more than 90% of oral cavity malignancies, the most common cancer being in this location in Brazil. Studies in the area focus on investigating the molecular basis of tumor development and progression. However, recent research investigates epigenetic changes as critical changes in carcinogenesis and, among these modifications, DNA methylation is included. PTEN gene ...
Immunohistochemical evaluation of GLUT-3 and GLUT-4 in oral epithelial dysplasi...
Feitosa, Sthefane Gomes; Viana, Khalil Fernandes; Luna, Ealber Carvalho Macedo; Costa, Fábio Wildson Gurgel; Cavalcante, Roberta BarrosoObjectives: To evaluate immunohistochemically the expression of GLUT-3 and GLUT-4 in oral epithelial dysplasia (OED) and the oral squamous cell carcinoma (OSCC) and assess possible involvement in the malignant transformation of oral lesions. Methods: Tissue samples of 15 cases of OSCC and 15 of OED were subjected to immunohistochemistry with anti-GLUT-3 and anti-GLUT-4 antibodies. Five fields of each case were ...
Unusual occurrence of tongue sensorial disorder after conservative surgical tre...
Sousa, Luane Macêdo de; Albuquerque, Assis Filipe Medeiros; Silva, Paulo Goberlânio Barros; Bezerra, Thâmara Manoela MarinhoLymphoepithelial cyst is a rare lesion of the oral cavity, with the mouth floor being the most common site of occurrence. The therapeutic approach of choice is the surgical treatment, which has rare cases of postoperative complications. The aim of this study is to report the case of a 53-year-old patient who came to Dental Service in the Federal University of Cear´a complaining of a small nodular lesion (0.5 cm...
Expressão imuno-histoquímica de cd133 em displasias epiteliais orais e carcinom...
Luna, Ealber Carvalho MacedoC ancer stem cells are a subpopulation of neoplastic cells, which have properties phenotypic differentiation, cell renewal and proliferation similar to normal stem cells are r esponsible for tumor support. Objective: To investigate the immunoreactivity of CD133, a marker of cancer stem cells in oral epithelial dysplasia and oral squamous cell carcinoma . Methods: 15 cases were selected as CEO and 15 cases of DE...