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Analysis of polymorphism of the APOBEC3G gene in HIV positive patients

Gomes, Julia do Amaral; Merino, Amanda Susin; Lunge, Vagner Ricardo; Simon, Daniel

Human immunodeficiency virus type 1 (HIV-1) is the etiologic agent of the current AIDS pandemic. Viral hepatitis B (HBV) and C (HCV) are highly prevalent in HIV-infected individuals. APOBEC3G (A3G) gene is a human genetic factor currently investigated in control of HIV-1 replication and progression of AIDS. Studies investigated its effect on HCV and HBV replication. APOBEC3G mediates changes that result in loss...

Date: 2022   |   Origin: Oasisbr

Use of DNA markers for genomic diagnosis of domestic animals: 1. Detection of p...

Garcia, José Fernando; Gurgel, André Sanches do Amaral; Visintin, José Antonio; Lunge, Vagner Ricardo; Hoetzel, Isidro

Ten Holstein bovines, descendants from Ivanhoe line, have been analyzed. DNAs, purified from leukocytes of those animals, were submitted to Polymerase Chain Reaction technique (PCR) and digested by Hae III and Taq I restriction enzymes. Accordingly, the bovine leukocyte adhesion deficiency (BLAD) genomic diagnosis was established. The tests revealed that 2 animals were carriers and 8 were normal. Since the deve...

Date: 1996   |   Origin: Oasisbr

Use of DNA markers for genomic diagnosis of domestic animals: 2. Detection of p...

Garcia, José Fernando; Gurgel, André Sanches do Amaral; Visintin, José Antonio; Lunge, Vagner Ricardo; Duarte, Marcelo Barbante; Bertolli, Jarbas Leonel

Twelve Quarter horses, descendants from Impressive line, have been analyzed. DNAs, purified from leukocytes of those animals, were submitted to Polymerase Chain Reaction technique (PCR) and digested by Taq I restrictionenzyme. Accordingly the Hyperkalemic Periodic Paralysis (HYPP) genomic diagnosis was established. The tests revealed that 9 animals were carrier heterozygotes (N/H) and 3 normal homozygotes (N/N)...

Date: 1996   |   Origin: Oasisbr

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