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Isoflavones as apoptosis inducers in human hepatoma HuH-7 cells.

Mansoor, T.A.; Ramalho, R.M.; Luo, X.; Ramalhete, Cátia; Rodrigues, C. M.; Ferreira, Maria José

Nine flavonoids isolated from the ethyl acetate extract of Pycnanthus angolensis were assayed for their potential apoptosis induction activities in human hepatoma HuH-7 cells. These flavonoids include eight isoflavones, namely irilone (1), tectorigenine (2), formononetin (3), genistein (4), 2'-hydroxybiochanin A (5), mixture of biochanin A (6) and prunetin (7), and 4',7-dihydroxy-2'-methoxyisoflavan (8), and th...

Date: 2018   |   Origin: Repositório Científico Atlântica
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