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Análise proteômica e funcional das diferenças sexo-específicas de neutrófilos q...
Luz, Isabelle SouzaDissertação (mestrado) — Universidade de Brasília, Faculdade de Medicina, Programa de Pós-Graduação em Patologia Molecular, 2021.; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES).; Como uma variável biológica, o sexo modula o sistema imunitário e pode estar envolvido nas diferenças observadas entre homens e mulheres de manifestação e desenvolvimento de doenças infecciosas, autoimunes e cânce...
Phosphoproteomic analysis of rat neutrophils shows the effect of intestinal isc...
Tahir, Muhammad; Arshid, Samina; Fontes, Belchor; Castro, Mariana S.; Sidoli, Simone; Schwämmle, Veit; Luz, Isabelle Souza; Roepstorff, PeterIntestinal ischemia reperfusion injury (iIRI) is a severe clinical condition presenting high morbidity and mortality worldwide. Some of the systemic consequences of IRI can be prevented by applying ischemic preconditioning (IPC), a series of short ischemia/reperfusion events preceding the major ischemia. Although neutrophils are key players in the pathophysiology of ischemic injuries, neither the dysregulation ...
Molecular and cellular biomarkers of COVID-19 prognosis : protocol for the pros...
Kurizky, Patricia Shu; Nóbrega, Otávio T.; Soares, Alexandre Anderson de Sousa Munhoz; Aires, Rodrigo Barbosa; Albuquerque, Cleandro Pires deBackground: Since the beginning of the COVID-19 pandemic, the world’s attention has been focused on better understanding the relation between the human host and the SARS-CoV-2 virus, as its action has led to hundreds of thousands of deaths. Objective: In this context, we decided to study certain consequences of the abundant cytokine release over the innate and adaptive immune systems, inflammation, and hemostas...