3 documents found, page 1 of 1
Embracing monogenic Parkinson's disease: the MJFF Global Genetic PD Cohort
Vollstedt, Eva‐Juliane; Schaake, Susen; Lohmann, Katja; Padmanabhan, Shalini; Brice, Alexis; Lesage, Suzanne; Tesson, Christelle; Vidailhet, MarieBackground: As gene-targeted therapies are increasingly being developed for Parkinson's disease (PD), identifying and characterizing carriers of specific genetic pathogenic variants is imperative. Only a small fraction of the estimated number of subjects with monogenic PD worldwide are currently represented in the literature and availability of clinical data and clinical trial-ready cohorts is limited. Objectiv...
Moving towards home-based community-centred integrated care in Parkinson's disease
Fabbri, Margherita; Caldas, Ana Castro; Ramos, Joana B.; Sanchez-Ferro, Álvaro; Antonini, Angelo; Růžička, Evžen; Lynch, Timothy; Rascol, OliverPeople living with Parkinson's disease (PwP) experience a wide range of motor and non-motor symptoms associated with increasing complexity of care delivery. A multispecialty approach has been presented as an intuitive solution for tailored and comprehensive care delivery. Nevertheless, past trials of both multidisciplinary or interdisciplinary care models in PD suggested no measurable change to a small benefit ...
Patient-centred management of Parkinson's disease
Grimes, David; Antonini, Angelo; Ferreira, Joaquim J; Sanchez-Ferro, Álvaro; Lynch, Timothy; Rascol, Oliver; Růžička, Evžen; Eggers, CarstenThe Personal View by Bloem and colleagues1 on integrated and patient-centred management of Parkinson's disease proposes a health system organisation to address complex care in chronic neurological disorders, using Parkinson's disease as an example. The proposed hub-and-spoke model envisions the integration of health professionals based on a Parkinson's disease centre of excellence integrated with community hosp...