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Osteopontin is upregulated in human and murine acute schistosomiasis mansoni
Thiago Almeidapereira; Rafal p Witek; William Evan Secor; Fausto Edmundo Lima Pereira; Jose Roberto Lambertucci; Anna Mae Diehl; Wing-kin SynBackground Symptomatic acute schistosomiasis mansoni is a systemic hypersensitivity reaction against the migrating schistosomula and mature eggs after a primary infection. The mechanisms involved in the pathogenesis of acute schistosomiasis are not fully elucidated. Osteopontin has been implicated in granulomatous reactions and in acute hepatic injury. Our aims were to evaluate if osteopontin plays a role in ac...
Data: 2022
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Origem: Oasisbr