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Use of aminoglycosides as a therapeutic strategy to fight infections caused by ...

Silva, Júlio Eduardo Barbosa da; Souza, Jaqueline Barbosa de; Macêdo, Daniel Charles dos Santos; Barros, Maria Clara de Sousa Arruda

The treatment of infections caused by enterobacteria that produce extended-spectrum β-lactamases enzymes (ESBLs) is increasingly challenging, so that the indiscriminate and exacerbated use of antibiotics has promoted bacterial resistance and dissemination of these pathogens, making the treatment of these bacteria a public health challenge. Taking into account that aminoglycosides are the antibiotics indicated f...

Date: 2022   |   Origin: Oasisbr

Analysis of financial sustainability to guarantee full access to cancer drugs

Rocha Filho, José de Arimatea; Matta, Carolina Barbosa Brito da; Silva, Thiago Douberin da; Paz Neta, Doralice Conceição da

The high incidence of cancer cases has made it an evident public health problem worldwide. Public network managers in Brazil claim that the funds transferred are not sufficient to cover the costs of chemotherapy. This work provided an overview of the service offered by the SUS in the oncology care network in Pernambuco and evaluated the financial sustainability to ensure access to chemotherapy drugs in a refere...

Date: 2021   |   Origin: Oasisbr

Advantages of using liposome-encapsulated antibiotics to fight infections cause...

Silva, Júlio Eduardo Barbosa da; Souza, Jaqueline Barbosa de; Macêdo, Daniel Charles dos Santos; Campos, Luís André de Almeida

Introduction: The treatment of diseases caused by enterobacteria is an increasing challenge. This problem results from the inefficiency of antibiotics to fight pathogens or to stimulate phagocytosis of cells of the reticuloendothelial system, mainly against bacteria that install and multiply inside phagocytic cells. Some antibiotics are ineffective at entering cells or have their capacity reduced by the plasma ...

Date: 2021   |   Origin: Oasisbr

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